Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5879657 | 0.89 | EGFR (0.37) | GAAKMT2AEGFR | |
| SCHEMBL5879694 | 0.75 | EGFR (0.41) | EGFR | |
| SCHEMBL5879509 | 0.66 | EGFR (0.41) | GAAKMT2AEGFR | |
| SCHEMBL5879532 | 0.64 | KDR (0.37) | KMT2A | |
| SCHEMBL1675990 | 0.59 | EGFR (0.56) | GAAKMT2AEGFR | |
| SCHEMBL2995782 | 0.58 | CASP3 (0.45) | KMT2A | |
| SCHEMBL3672992 | 0.57 | MAPT (0.40) | GAA | |
| SCHEMBL28482431 | 0.57 | KMT2A (0.45) | GAAKMT2AEGFR | |
| SCHEMBL2990451 | 0.57 | KMT2A (0.50) | GAAKMT2A | |
| SCHEMBL30037218 | 0.57 | KMT2A (0.45) | GAAKMT2AEGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7105508-B1 | Integrin receptors antagonists | ABBOTT GMBH & CO. KG (DE) | 2006-09-12 | — | — | US | disclosed |