Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | JAK2 | O60674 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5879504 | 0.89 | GAA (0.34) | EGFRGAAKMT2A | |
| SCHEMBL5879694 | 0.88 | EGFR (0.41) | EGFRTSHRALDH1A1KDRPOLB | |
| SCHEMBL5879532 | 0.76 | KDR (0.37) | TSHRALDH1A1KDRKMT2A | |
| SCHEMBL5879509 | 0.72 | EGFR (0.41) | EGFRTSHRALDH1A1SMN1; SMN2GAA | |
| SCHEMBL5879566 | 0.68 | ITGB3 (0.54) | POLB | |
| SCHEMBL1675990 | 0.67 | EGFR (0.56) | EGFRTSHRPOLBGAAKMT2A | |
| SCHEMBL1388649 | 0.64 | EGFR (0.60) | EGFRTSHRALDH1A1SMN1; SMN2GAA | |
| SCHEMBL6305777 | 0.63 | EGFR (0.43) | EGFRTSHRALDH1A1SMN1; SMN2POLB | |
| SCHEMBL38650796 | 0.63 | EGFR (0.43) | EGFRALDH1A1HTT | |
| SCHEMBL859822 | 0.62 | ALDH1A1 (0.47) | ALDH1A1KDRPOLBGAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7105508-B1 | Integrin receptors antagonists | ABBOTT GMBH & CO. KG (DE) | 2006-09-12 | — | — | US | disclosed |