Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MECP2 | P51608 | 1/20 | 0.60 |
| ▸ | KCNN1 | Q92952 | 1/20 | 0.60 |
| ▸ | KCNN2 | Q9H2S1 | 1/20 | 0.60 |
| ▸ | MBD2 | Q9UBB5 | 1/20 | 0.60 |
| ▸ | KCNN3 | Q9UGI6 | 1/20 | 0.60 |
| ▸ | NPC1 | O15118 | 16/20 | 0.58 |
| ▸ | RAB9A | P51151 | 15/20 | 0.58 |
| ▸ | MEN1 | O00255 | 12/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 12/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.57 |
| ▸ | MAPT | P10636 | 5/20 | 0.57 |
| ▸ | TP53 | P04637 | 3/20 | 0.57 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.57 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.57 |
| ▸ | RELA | Q04206 | 3/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | GAA | P10253 | 3/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24102119 | 0.81 | MECP2 (0.56) | MECP2KCNN1KCNN2MBD2KCNN3 | |
| SCHEMBL5897541 | 0.77 | MECP2 (0.51) | MECP2KCNN1KCNN2MBD2KCNN3 | |
| SCHEMBL22639923 | 0.77 | PDE5A (0.55) | MECP2KCNN1KCNN2MBD2KCNN3 | |
| SCHEMBL12215995 | 0.76 | RAB9A (0.65) | MECP2KCNN1KCNN2MBD2KCNN3 | |
| SCHEMBL5879619 | 0.76 | MEN1 (0.55) | MECP2KCNN1KCNN2MBD2KCNN3 | |
| SCHEMBL24101942 | 0.76 | PDE5A (0.51) | MECP2KCNN1KCNN2MBD2KCNN3 | |
| SCHEMBL5155715 | 0.75 | KCNN1 (1.00) | MECP2KCNN1KCNN2MBD2KCNN3 | |
| SCHEMBL30745771 | 0.75 | KCNN1 (1.00) | MECP2KCNN1KCNN2MBD2KCNN3 | |
| SCHEMBL7552748 | 0.75 | NPC1 (0.91) | MECP2KCNN1KCNN2MBD2KCNN3 | |
| SCHEMBL27800934 | 0.75 | MECP2 (0.77) | MECP2KCNN1KCNN2MBD2KCNN3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7125883-B1 | Integrin receptor ligands | ABBOTT GMBH & CO. KG (DE) | 2006-10-24 | — | — | US | disclosed |
| US-7105508-B1 | Integrin receptors antagonists | ABBOTT GMBH & CO. KG (DE) | 2006-09-12 | — | — | US | disclosed |
| EP-1202988-A2 | NOVEL INTEGRIN RECEPTOR ANTAGONISTS | BASF AKTIENGESELLSCHAFT (DE) | 2002-05-08 | — | — | EP | disclosed |
| WO-2001010847-A2 | NOVEL INTEGRIN RECEPTOR ANTAGONISTS | BASF AKTIENGESELLSCHAFT (DE) | 2001-02-15 | — | — | WO | disclosed |