Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 11/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 11/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | POLB | P06746 | 3/20 | 0.52 |
| ▸ | MECP2 | P51608 | 1/20 | 0.50 |
| ▸ | KCNN1 | Q92952 | 1/20 | 0.50 |
| ▸ | KCNN2 | Q9H2S1 | 1/20 | 0.50 |
| ▸ | MBD2 | Q9UBB5 | 1/20 | 0.50 |
| ▸ | KCNN3 | Q9UGI6 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 12/20 | 0.49 |
| ▸ | RAB9A | P51151 | 11/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | TP53 | P04637 | 3/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.48 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.48 |
| ▸ | RELA | Q04206 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5879523 | 0.76 | MECP2 (0.60) | MEN1KMT2AALDH1A1MAPTPOLB | |
| SCHEMBL24102119 | 0.76 | MECP2 (0.56) | MEN1KMT2AALDH1A1MAPTPOLB | |
| SCHEMBL18342110 | 0.75 | MEN1 (0.49) | MEN1KMT2AALDH1A1PKMMAPT | |
| SCHEMBL23027787 | 0.74 | POLB (0.84) | MEN1KMT2AALDH1A1PKMMAPT | |
| SCHEMBL30711693 | 0.72 | ALDH1A1 (1.00) | MEN1KMT2AALDH1A1PKMMAPT | |
| SCHEMBL2959641 | 0.72 | ALDH1A1 (1.00) | MEN1KMT2AALDH1A1PKMMAPT | |
| SCHEMBL12271588 | 0.72 | ALDH1A1 (0.51) | MEN1KMT2AALDH1A1PKMMAPT | |
| SCHEMBL3147864 | 0.72 | ALDH1A1 (0.51) | MEN1KMT2AALDH1A1PKMMAPT | |
| SCHEMBL19762475 | 0.72 | PKM (0.74) | MEN1KMT2AALDH1A1PKMMAPT | |
| SCHEMBL22639923 | 0.72 | PDE5A (0.55) | MEN1KMT2AALDH1A1MAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7105508-B1 | Integrin receptors antagonists | ABBOTT GMBH & CO. KG (DE) | 2006-09-12 | — | — | US | disclosed |