Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 18/20 | 0.52 |
| ▸ | ITGAV | P06756 | 18/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5879905 | 0.84 | ITGB3 (0.72) | ITGB3ITGAV | |
| SCHEMBL5879655 | 0.68 | ITGB3 (0.84) | ITGB3ITGAV | |
| SCHEMBL5879558 | 0.64 | ITGB3 (0.74) | ITGB3ITGAVKDM4E | |
| SCHEMBL5879678 | 0.64 | ITGB3 (1.00) | ITGB3ITGAV | |
| SCHEMBL5879612 | 0.63 | GPR35 (0.34) | TSHR | |
| SCHEMBL5879551 | 0.63 | ITGB3 (0.83) | ITGB3ITGAV | |
| SCHEMBL3136524 | 0.61 | CYP1A2 (0.56) | TSHR | |
| SCHEMBL6701634 | 0.61 | NR1H3 (0.44) | TSHRSMN1; SMN2KDM4E | |
| SCHEMBL5879560 | 0.61 | ITGB3 (0.65) | ITGB3ITGAV | |
| SCHEMBL5879645 | 0.60 | ITGB3 (0.61) | ITGB3ITGAVTSHRSMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7105508-B1 | Integrin receptors antagonists | ABBOTT GMBH & CO. KG (DE) | 2006-09-12 | — | — | US | disclosed |