Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPBWR1 | P48145 | 1/20 | 0.58 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.57 |
| ▸ | GUSB | P08236 | 11/20 | 0.54 |
| ▸ | NT5E | P21589 | 1/20 | 0.51 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | APEX1 | P27695 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24074249 | 0.86 | HPSE (0.58) | NPBWR1HPSEGUSBCHEK2KDM4E | |
| SCHEMBL13373255 | 0.83 | NPBWR1 (0.43) | NPBWR1HPSEGUSBKDM4EMEN1 | |
| SCHEMBL6325549 | 0.83 | ALDH1A1 (0.68) | NPBWR1HPSEGUSBNT5EKDM4E | |
| SCHEMBL25722414 | 0.82 | HPSE (0.64) | NPBWR1HPSEGUSBCHEK2MEN1 | |
| SCHEMBL24619180 | 0.81 | NPBWR1 (0.50) | NPBWR1NT5ECHEK2KDM4EMEN1 | |
| SCHEMBL3333916 | 0.80 | GUSB (0.79) | NPBWR1HPSEGUSBCHEK2KDM4E | |
| SCHEMBL24075313 | 0.80 | HPSE (0.61) | HPSEGUSBKDM4EALDH1A1MAPT | |
| SCHEMBL7393557 | 0.80 | GUSB (0.79) | NPBWR1HPSEGUSBAMY1AGAA | |
| SCHEMBL3337332 | 0.79 | METAP2 (0.62) | HPSEGUSBKDM4EMEN1ALDH1A1 | |
| SCHEMBL28179657 | 0.79 | HPSE (0.60) | HPSEGUSBAMY1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7105508-B1 | Integrin receptors antagonists | ABBOTT GMBH & CO. KG (DE) | 2006-09-12 | — | — | US | disclosed |