Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | DAO | P14920 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ELANE | P08246 | 1/20 | 0.35 |
| ▸ | RIPK1 | Q13546 | 5/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.33 |
| ▸ | PLK1 | P53350 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17967930 | 0.81 | HSD17B10 (0.47) | LMNAL3MBTL1KDM4ENPC1RAB9A | |
| SCHEMBL4454368 | 0.80 | L3MBTL1 (0.41) | LMNAL3MBTL1RAB9AELANEKMT2A | |
| SCHEMBL251109 | 0.76 | LMNA (0.53) | LMNAKDM4ENPC1RAB9ASMN1; SMN2 | |
| SCHEMBL11001631 | 0.73 | PARP1 (0.36) | DAOKDM4ENPC1RAB9ASMN1; SMN2 | |
| SCHEMBL523396 | 0.72 | PIN1 (0.42) | LMNAL3MBTL1DAOKDM4ESMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL2816871 | 0.71 | PIN1 (0.41) | LMNAL3MBTL1DAOKDM4ESMN1; SMN2 | |
| SCHEMBL3368051 | 0.69 | MAP2K1 (0.48) | LMNAL3MBTL1KDM4ENPC1RAB9A | |
| SCHEMBL5315369 | 0.69 | DAO (0.37) | LMNADAOKDM4ENPC1RAB9A | |
| SCHEMBL11766590 | 0.68 | MAP2K1 (0.44) | LMNAKDM4ENPC1RAB9ASMN1; SMN2 | |
| SCHEMBL11768642 | 0.68 | KMT2A (0.46) | LMNAL3MBTL1KDM4ENPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7105508-B1 | Integrin receptors antagonists | ABBOTT GMBH & CO. KG (DE) | 2006-09-12 | — | — | US | disclosed |
| EP-1202988-A2 | NOVEL INTEGRIN RECEPTOR ANTAGONISTS | BASF AKTIENGESELLSCHAFT (DE) | 2002-05-08 | — | — | EP | disclosed |
| WO-2001010847-A2 | NOVEL INTEGRIN RECEPTOR ANTAGONISTS | BASF AKTIENGESELLSCHAFT (DE) | 2001-02-15 | — | — | WO | disclosed |