Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARL | Q9H300 | 3/20 | 0.36 |
| ▸ | MGLL | Q99685 | 2/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7524687 | 0.82 | PARL (0.38) | PARLMGLLALOX12 | |
| SCHEMBL4618888 | 0.78 | GLA (0.32) | PARLMGLL | |
| Bicarbonate SCHEMBL28277653 | 0.75 | MGLL (0.36) | PARLMGLLALOX12KMT2A | |
| Bicarbonate SCHEMBL28277654 | 0.75 | MGLL (0.36) | PARLMGLLALOX12KMT2A | |
| SCHEMBL118685 | 0.75 | PARL (0.41) | PARLMGLLALOX12KMT2A | |
| SCHEMBL865136 | 0.74 | MGLL (0.40) | PARLMGLLALOX12KMT2A | |
| SCHEMBL17447 | 0.74 | MGLL (0.37) | PARLMGLLALOX12 | |
| SCHEMBL15321160 | 0.73 | MGLL (0.36) | PARLMGLLALOX12KMT2A | |
| SCHEMBL2826280 | 0.73 | MGLL (0.30) | MGLL | |
| SCHEMBL3276680 | 0.72 | MGLL (0.36) | PARLMGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2006522140-A | — | — | 2006-09-28 | — | — | JP | claimed |
| EP-1608380-A2 | POLYMERIC DRUG AGENTS FOR THE TREATMENT OF FIBROTIC DISORDERS | Vectramed, Inc. (US) | 2005-12-28 | — | — | EP | claimed |
| WO-2004089311-A2 | POLYMERIC DRUG AGENTS FOR THE TREATMENT OF FIBROTIC DISORDERS | VECTRAMED, INC. (US) | 2004-10-21 | — | — | WO | claimed |
| EP-1176985-A2 | ENZYMATICALLY ACTIVATED POLYMERIC DRUG CONJUGATES | Vectramed, Inc. (US) | 2002-02-06 | — | — | EP | disclosed |
| WO-2000064486-A2 | ENZYMATICALLY ACTIVATED POLYMERIC DRUG CONJUGATES | VECTRAMED, INC. (US) | 2000-11-02 | — | — | WO | disclosed |