Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALPI | P09923 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.50 |
| ▸ | XIAP | P98170 | 1/20 | 0.50 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.47 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.47 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.46 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | PPARA | Q07869 | 1/20 | 0.44 |
| ▸ | CPA1 | P15085 | 5/20 | 0.43 |
| ▸ | CPA3 | P15088 | 2/20 | 0.43 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.43 |
| ▸ | CPB1 | P15086 | 1/20 | 0.43 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.43 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11130925 | 0.82 | MTNR1A (0.50) | ALPIPKMPTGS1XIAPSLC7A5 | |
| SCHEMBL5880392 | 0.82 | HKDC1 (0.47) | MTNR1AMTNR1BPDPK1MEN1POLB | |
| SCHEMBL28305706 | 0.78 | CNR2 (0.49) | ALPIPKMPTGS1XIAPSLC7A5 | |
| SCHEMBL2835490 | 0.77 | CYP1A2 (0.53) | ALPIPKMPTGS1XIAPSLC7A5 | |
| SCHEMBL262279 | 0.77 | CYP1A2 (0.53) | ALPIPKMPTGS1XIAPSLC7A5 | |
| SCHEMBL5292778 | 0.75 | SLC1A3 (0.62) | ALPIPKMPTGS1XIAPSLC7A5 | |
| SCHEMBL8761504 | 0.74 | EPHX1 (0.52) | CYP1A2EPHX1MDM2CYP2C19CYP2D6 | |
| SCHEMBL5272849 | 0.74 | EPHX1 (0.67) | ALPIPKMPTGS1XIAPSLC7A5 | |
| SCHEMBL7283137 | 0.74 | CYP2D6 (0.45) | PTGS1PDPK1KDM4EMAPTRECQL | |
| SCHEMBL9833991 | 0.74 | ALPI (0.61) | ALPIPKMPTGS1XIAPSLC7A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4826815-A | HYPOTENSIVE | ABBOTT LABORATORIES (US) | 1989-05-02 | — | — | US | disclosed |