Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.66 |
| ▸ | TP53 | P04637 | 3/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.49 |
| ▸ | AGER | Q15109 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | TAS2R14 | Q9NYV8 | 2/20 | 0.47 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.46 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11582455 | 0.91 | HSD11B1 (0.81) | HSD11B1TP53MAPTLMNAALDH1A1 | |
| SCHEMBL27177337 | 0.82 | ALDH1A1 (0.57) | HSD11B1MAPTLMNAALDH1A1MCOLN3 | |
| SCHEMBL27925640 | 0.82 | PAX8 (0.56) | HSD11B1TP53MAPTLMNAALDH1A1 | |
| SCHEMBL29065272 | 0.81 | ALDH1A1 (0.55) | HSD11B1MAPTLMNAALDH1A1MCOLN3 | |
| SCHEMBL11326000 | 0.81 | KEAP1 (0.57) | HSD11B1MAPTLMNAALDH1A1MCOLN3 | |
| SCHEMBL27773249 | 0.80 | HSD11B1 (0.48) | HSD11B1TP53LMNAALDH1A1MCOLN3 | |
| SCHEMBL26680105 | 0.79 | HSD11B1 (1.00) | HSD11B1MAPTLMNAALDH1A1KDM4E | |
| SCHEMBL13492300 | 0.79 | HSD11B1 (0.47) | HSD11B1TP53MAPTLMNAALDH1A1 | |
| SCHEMBL27794539 | 0.79 | MAPT (0.47) | HSD11B1TP53MAPTLMNAALDH1A1 | |
| SCHEMBL26657619 | 0.79 | ALDH1A1 (0.50) | HSD11B1TP53MAPTLMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7153925-B2 | Condensation polymers from N, N*-disubstituted disulfonamides | PEWS R GARTH | 2006-12-26 | — | — | US | disclosed |
| US-20060128924-A1 | Novel condensation polymers from N, N*-disubstituted disulfonamides | PEWS R G | 2006-06-15 | — | — | US | disclosed |