Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 4/20 | 0.43 |
| ▸ | ESR1 | P03372 | 6/20 | 0.42 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 2/20 | 0.37 |
| ▸ | CA12 | O43570 | 3/20 | 0.37 |
| ▸ | CA1 | P00915 | 3/20 | 0.37 |
| ▸ | CA9 | Q16790 | 3/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | MMP3 | P08254 | 1/20 | 0.37 |
| ▸ | MMP7 | P09237 | 1/20 | 0.37 |
| ▸ | MMP9 | P14780 | 1/20 | 0.37 |
| ▸ | MMP8 | P22894 | 1/20 | 0.37 |
| ▸ | MMP14 | P50281 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | PPARD | Q03181 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1374250 | 0.85 | ALDH1A1 (0.47) | KMT2ACA2GAALMNACA12 | |
| SCHEMBL30811038 | 0.83 | PLCG1 (0.48) | KMT2ACA2GAALMNACA12 | |
| SCHEMBL30811026 | 0.83 | CA12 (0.44) | KMT2ACA2GAALMNACA12 | |
| SCHEMBL23732506 | 0.83 | GAA (0.55) | CA2GAALMNACA12CA1 | |
| SCHEMBL31248447 | 0.83 | CA12 (0.44) | KMT2ACA2CA12CA1CA9 | |
| SCHEMBL1396563 | 0.83 | PSIP1 (0.53) | CA2LMNACA12CA1CA9 | |
| SCHEMBL31389230 | 0.81 | HSD17B1 (0.40) | KMT2ACA2ESR1GAAPKM | |
| SCHEMBL30049375 | 0.80 | CA2 (0.54) | KMT2ACA2PKMCA12CA1 | |
| SCHEMBL21723650 | 0.78 | ALDH1A1 (0.55) | KMT2AGAATSHR | |
| SCHEMBL27666418 | 0.78 | KMT2A (0.36) | KMT2AESR1GAATSHRPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12234207-B2 | Halo-(3-(phenylsulfonyl)prop-1-enyl)pyridine derivative and use thereof | CUREVERSE INCORPORATED (KR) | 2025-02-25 | — | — | US | disclosed |
| US-20210317083-A1 | NOVEL HALO-(3-(PHENYLSULFONYL)PROP-1-ENYL)PYRIDINE DERIVATIVE AND USE THEREOF | CUREVERSE INCORPORATED (KR) | 2021-10-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210317083-A1 | NOVEL HALO-(3-(PHENYLSULFONYL)PROP-1-ENYL)PYRIDINE DERIVATIVE AND USE THEREOF | KEAP1, NFE2L2, BACH1 | KMT2A 2410/4885CA2 3035/4885ESR1 3651/4885 |
| US-12234207-B2 | Halo-(3-(phenylsulfonyl)prop-1-enyl)pyridine derivative and use thereof | KEAP1, NFE2L2, NQO1 | KMT2A 2452/4885CA2 3156/4885ESR1 3266/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.