SCHEMBL5881248

SCHEMBL5881248

CCCCCCCCCCCCCCCC=CC1CNC(CCO)=N1

nearest known ligand 0.34

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TNNC1 P63316 1/20 0.32
EPHX2 P34913 1/20 0.31
GMNN O75496 1/20 0.31
USP2 O75604 1/20 0.31
LMNA P02545 1/20 0.31
CYP1A2 P05177 1/20 0.31
POLB P06746 1/20 0.31
MAPT P10636 1/20 0.31
CYP2C9 P11712 1/20 0.31
ALOX15 P16050 1/20 0.31
APEX1 P27695 1/20 0.31
CYP2C19 P33261 1/20 0.31
RECQL P46063 1/20 0.31
BLM P54132 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
HSD17B10 Q99714 1/20 0.31
DUSP3 P51452 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11204048 0.90 FAAH (0.33) EPHX2GMNNUSP2LMNACYP1A2
SCHEMBL11342438 0.86 HTR2A (0.32) CYP1A2CYP2C19
SCHEMBL217509 0.80 EPHX2 (0.35) EPHX2GMNNUSP2LMNACYP1A2
SCHEMBL611384 0.80 ALDH1A1 (0.37) EPHX2GMNNUSP2LMNACYP1A2
SCHEMBL6161362 0.77 CCR5 (0.36)
SCHEMBL769186 0.76 DEGS1 (0.34) EPHX2LMNA
SCHEMBL4609636 0.76 TERT (0.42) GMNNUSP2LMNACYP1A2POLB
SCHEMBL7158875 0.75 EPHX2 (0.38) EPHX2GMNNUSP2LMNACYP1A2
SCHEMBL9098243 0.75 EPHX2 (0.38) EPHX2GMNNUSP2LMNACYP1A2
SCHEMBL5629600 0.75 ABCG2 (0.37) GMNNLMNACYP1A2POLBMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7060335-B2 Recording medium, method of manufacturing the same and image forming method CANON KABUSHIKI KAISHA (JP) 2006-06-13 US disclosed