Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 6/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6625108 | 0.88 | PDGFRB (0.50) | ALDH1A1MAPTHTTTSHRNPC1 | |
| SCHEMBL5881333 | 0.83 | TSHR (0.46) | ALDH1A1MAPTHTTTSHRNPC1 | |
| SCHEMBL6622852 | 0.77 | SMN1; SMN2 (0.48) | ALDH1A1MAPTHTTNPC1RAB9A | |
| SCHEMBL6994833 | 0.76 | CASP1 (0.51) | ALDH1A1MAPTHTTTSHRNPC1 | |
| SCHEMBL28050912 | 0.73 | TSHR (0.77) | ALDH1A1MAPTTSHRNPC1RAB9A | |
| SCHEMBL6753052 | 0.73 | ALDH1A1 (0.50) | ALDH1A1MAPTHTTNPC1RAB9A | |
| SCHEMBL27576986 | 0.73 | TSHR (0.52) | ALDH1A1MAPTHTTTSHRNPC1 | |
| SCHEMBL6625444 | 0.72 | ALDH1A1 (0.50) | ALDH1A1MAPTHTTNPC1RAB9A | |
| SCHEMBL22230097 | 0.71 | ALDH1A1 (0.64) | ALDH1A1MAPTHTTNPC1RAB9A | |
| SCHEMBL6625315 | 0.70 | ALDH1A1 (0.52) | ALDH1A1MAPTNPC1RAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7053082-B1 | 2,3-benzodiazepine derivatives | EGIS GYOGYSZERGYAR RT. (HU) | 2006-05-30 | — | — | US | disclosed |
| EP-1200442-B1 | 2,3-BENZODIAZEPINE DERIVATIVES | EGIS GY GYSZERGY R RT (HU) | 2003-06-25 | — | — | EP | disclosed |