SCHEMBL588405

SCHEMBL588405

O=C(O)c1ccc(I)cc1I

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 2/20 0.48
PTPRC P08575 1/20 0.48
PTPN2 P17706 1/20 0.48
PTPRA P18433 1/20 0.48
PTPRB P23467 1/20 0.48
PTPRE P23469 1/20 0.48
PTPN6 P29350 1/20 0.48
TPMT P51580 2/20 0.46
CYP1A2 P05177 1/20 0.46
MAP2K1 Q02750 3/20 0.44
MAP2K2 P36507 1/20 0.44
MAOB P27338 1/20 0.42
ALDH1A1 P00352 3/20 0.41
TSHR P16473 2/20 0.41
CA12 O43570 1/20 0.41
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
CA7 P43166 1/20 0.41
CA9 Q16790 1/20 0.41
CA14 Q9ULX7 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL522679 0.83 PTPN1 (0.55) PTPN1PTPRCPTPN2PTPRAPTPRB
SCHEMBL1277864 0.81 PTPRC (0.53) PTPN1PTPRCPTPN2PTPRAPTPRB
SCHEMBL15128910 0.79 CA12 (0.61) PTPN1CYP1A2ALDH1A1TSHRCA12
SCHEMBL980376 0.79 ALDH1A1 (0.61) PTPN1PTPRCPTPN2PTPRAPTPRB
SCHEMBL6645457 0.79 TPMT (0.54) PTPN1TPMTCYP1A2ALDH1A1TSHR
SCHEMBL28879905 0.79 TTR (0.39) PTPN1PTPRCPTPN2PTPRAPTPRB
SCHEMBL499643 0.77 SMN1; SMN2 (0.63) CYP1A2ALDH1A1TSHRCA1CA2
SCHEMBL1588995 0.77 KEAP1 (0.53) CYP1A2ALDH1A1TSHRCA12CA1
SCHEMBL12302451 0.77 KDM4E (0.53) CYP1A2GRIK1ALOX15CASP1KDM4E
SCHEMBL9741686 0.77 CSNK2A1 (0.55) CYP1A2MAOBALDH1A1CA12CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 76 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108947856-A A kind of preparation method of iodo- 4 aminoanisole of 2- 南京卡邦科技有限公司 2018-12-07 CN claimed
US-20070123622-A1 ETHER-ESTER PLASTICIZERS FERRO CORPORATION (US) 2007-05-31 US claimed
EP-1456322-A4 GLYCERIN TRIESTER PLASTICIZER FERRO CORP (US) 2005-03-16 EP claimed
EP-1456322-A1 GLYCERIN TRIESTER PLASTICIZER FERRO CORPORATION (US) 2004-09-15 EP claimed
WO-2003054106-A1 GLYCERIN TRIESTER PLASTICIZER FERRO CORPORATION (US) 2003-07-03 WO claimed
US-20030116750-A1 Glycerin triester plasticizer POLYMER ADDITIVES, INC. 2003-06-26 US claimed
WO-2025072511-A1 TAILORING NON-EQUILIBRIUM PATHWAYS FOR THE SELECTIVE FORMATION OF INTERMEDIATE COMPOUNDS BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2025-04-03 WO disclosed
US-12146028-B2 Iodo-functionalized polymers as mass spectrometry calibrants with a mass-defect offset POLYMER FACTORY SWEDEN AB (SE) 2024-11-19 US disclosed
US-20240241444-A1 ACTINIC RAY-SENSITIVE OR RADIATION-SENSITIVE RESIN COMPOSITION, ACTINIC RAY-SENSITIVE OR RADIATION-SENSITIVE FILM, PATTERN FORMING METHOD, AND METHOD FOR MANUFACTURING ELECTRONIC DEVICE FUJIFILM CORPORATION (JP) 2024-07-18 US disclosed
US-20230384676-A1 RADIATION-SENSITIVE RESIN COMPOSITION, METHOD OF FORMING PATTERN, POLYMER, AND COMPOUND JSR CORPORATION (JP) 2023-11-30 US disclosed
US-20230384676-A1 RADIATION-SENSITIVE RESIN COMPOSITION, METHOD OF FORMING PATTERN, POLYMER, AND COMPOUND JSR CORPORATION (JP) 2023-11-30 US disclosed
US-11829068-B2 Resist composition, method of forming resist pattern, compound, and resin TOKYO OHKA KOGYO CO., LTD. (JP) 2023-11-28 US disclosed
US-11829068-B2 Resist composition, method of forming resist pattern, compound, and resin TOKYO OHKA KOGYO CO., LTD. (JP) 2023-11-28 US disclosed
US-20030216577-A1 Preparation of aromatic and heteroaromatic carboxylic acids by catalytic ozonolysis DSM FINE CHEMICALS AUSTRIA NFG GMBH & COKG (AT) 2003-11-20 US disclosed
EP-1362840-A1 Process for the preparation of aromatic and heteroaromatic carboxylic acids via catalytic ozonolysis DSM Fine Chemicals Austria Nfg GmbH & Co KG (AT) 2003-11-19 EP disclosed
WO-2003054106-A1 GLYCERIN TRIESTER PLASTICIZER FERRO CORPORATION (US) 2003-07-03 WO disclosed
US-20030120104-A1 Glycerin triester plasticizer FERRO CORPORATION (US) 2003-06-26 US disclosed
US-20030116750-A1 Glycerin triester plasticizer POLYMER ADDITIVES, INC. 2003-06-26 US disclosed
US-20030086869-A1 Methods and kits for diagnosing a pancreatic-based fat malabsorption disorder THE CHILDREN'S HOSPITAL OF PHILADELPHIA 2003-05-08 US disclosed
WO-2002099123-A1 METHODS AND KITS FOR DIAGNOSING A PANCREATIC-BASED FAT MALABSORPTION DISORDER THE CHILDREN'S HOSPITAL OF PHILADELPHIA (US) 2002-12-12 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230384676-A1 RADIATION-SENSITIVE RESIN COMPOSITION, METHOD OF FORMING PATTERN, POLYMER, AND COMPOUND RER1, RFT1, RAD51 PTPN1 4336/4885PTPRC 4797/4885PTPN2 4694/4885
US-20030086869-A1 Methods and kits for diagnosing a pancreatic-based fat malabsorption disorder PNLIP, FABP2, FABP6 PTPN1 3407/4885PTPRC 1859/4885PTPN2 3629/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.