Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.59 |
| ▸ | TDO2 | P48775 | 2/20 | 0.59 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.52 |
| ▸ | SCN4A | P35499 | 2/20 | 0.50 |
| ▸ | DPP4 | P27487 | 2/20 | 0.48 |
| ▸ | F2 | P00734 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.46 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.46 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.45 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL587761 | 1.00 | IDO1 (0.59) | IDO1TDO2ADRB2SCN4ADPP4 | |
| SCHEMBL588076 | 1.00 | IDO1 (0.59) | IDO1TDO2ADRB2SCN4ADPP4 | |
| Hydrochloric Acid SCHEMBL1143208 | 0.98 | IDO1 (0.61) | IDO1TDO2ADRB2SCN4ADPP4 | |
| Hydrochloric Acid SCHEMBL3998446 | 0.95 | IDO1 (0.55) | IDO1TDO2ADRB2SCN4ADPP4 | |
| SCHEMBL1732927 | 0.89 | ADRB2 (0.62) | IDO1TDO2ADRB2TSHRHIF1A | |
| Hydrochloric Acid SCHEMBL3179658 | 0.87 | ADRB2 (0.59) | IDO1TDO2ADRB2TSHRHIF1A | |
| SCHEMBL11480062 | 0.87 | DPP4 (0.61) | DPP4F2TSHRHIF1AADRA2A | |
| SCHEMBL11478580 | 0.87 | DPP4 (0.61) | DPP4F2TSHRHIF1AADRA2A | |
| Aminodiphenylmethane SCHEMBL7841 | 0.84 | DPP4 (0.65) | DPP4F2TSHRHIF1AADRA2A | |
| Aminodiphenylmethane SCHEMBL7719817 | 0.81 | DPP4 (0.55) | DPP4F2TSHRHIF1AADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110950821-B | Preparation method of levocetirizine | 湖南九典宏阳制药有限公司 | 2020-05-15 | — | — | CN | claimed |
| CN-110950821-A | Preparation method of levocetirizine | 湖南九典宏阳制药有限公司 | 2020-04-03 | — | — | CN | claimed |
| CN-103044355-A | Key intermediate for synthesizing levocetirizine and preparation method thereof | HUNAN JIUDIAN PHARMACEUTICAL CO LTD | 2013-04-17 | — | — | CN | claimed |
| CN-103044356-A | New method for synthesizing levocetirizine and key intermediate thereof | HUNAN JIUDIAN PHARMACEUTICAL CO LTD | 2013-04-17 | — | — | CN | claimed |
| US-7851627-B2 | Optically active carbamates, process for preparation thereof and use thereof as pharmaceutical intermediates | EGIS GYOGYSZERGYAR NYILVANOSAN MUKODO RESZVENYTARSASAG (HU) | 2010-12-14 | — | — | US | claimed |
| US-20090221823-A1 | OPTICALLY ACTIVE CARBAMATES, PROCESS FOR PREPARATION THEREOF AND USE THEREOF AS PHARMACEUTICAL INTERMEDIATES | EGIS GYOGYSZERGYAR NYILVANOSAN MUKODO RESZVENYTARSASAG (HU) | 2009-09-03 | — | — | US | claimed |
| EP-1963296-A2 | OPTICALLY ACTIVE CARBAMATES, PROCESS FOR PREPARATION THEREOF AND USE THEREOF AS PHARMACEUTICAL INTERMEDIATES | Egis Gyógyszergyár Nyilvánosan Múködö Részvénytársaság (HU) | 2008-09-03 | — | — | EP | claimed |
| WO-2007066163-A2 | OPTICALLY ACTIVE CARBAMATES, PROCESS FOR PREPARATION THEREOF AND USE THEREOF AS PHARMACEUTICAL INTERMEDIATES | Egis Gyógyszergyár Nyilvanosan Mukodo Reszvenytarsasag (HU) | 2007-06-14 | — | — | WO | claimed |
| CN-110950821-B | Preparation method of levocetirizine | 湖南九典宏阳制药有限公司 | 2020-05-15 | — | — | CN | disclosed |
| CN-110950821-B | Preparation method of levocetirizine | 湖南九典宏阳制药有限公司 | 2020-05-15 | — | — | CN | disclosed |
| CN-110950821-A | Preparation method of levocetirizine | 湖南九典宏阳制药有限公司 | 2020-04-03 | — | — | CN | disclosed |
| CN-110950821-A | Preparation method of levocetirizine | 湖南九典宏阳制药有限公司 | 2020-04-03 | — | — | CN | disclosed |
| EP-3283622-B1 | MUTANT TRANSAMINASES AS WELL AS METHODS AND USES RELATING THERETO | HOFFMANN LA ROCHE (CH) | 2019-07-03 | — | — | EP | disclosed |
| US-10322122-B2 | Methods and compositions for treating degenerative and ischemic disorders | THE GENERAL HOSPITAL CORPORATION (US) | 2019-06-18 | — | — | US | disclosed |
| EP-1963296-A2 | OPTICALLY ACTIVE CARBAMATES, PROCESS FOR PREPARATION THEREOF AND USE THEREOF AS PHARMACEUTICAL INTERMEDIATES | Egis Gyógyszergyár Nyilvánosan Múködö Részvénytársaság (HU) | 2008-09-03 | — | — | EP | disclosed |
| WO-2007066163-A2 | OPTICALLY ACTIVE CARBAMATES, PROCESS FOR PREPARATION THEREOF AND USE THEREOF AS PHARMACEUTICAL INTERMEDIATES | Egis Gyógyszergyár Nyilvanosan Mukodo Reszvenytarsasag (HU) | 2007-06-14 | — | — | WO | disclosed |
| CN-1970549-A | Chiral benzhydryl piperazine derivatives and its preparation method | UNIV GUANGXI (CN) | 2007-05-30 | — | — | CN | disclosed |
| US-5171865-A | Process for the preparation of optically active 4-oxo-1-benzopyran-2-carboxylic acid derivatives and intermediates thereof | SANWA KAGAKU KENKYUSHO CO., LTD. (JP) | 1992-12-15 | — | — | US | disclosed |
| CN-1035827-A | The 4-oxo of opticity-1-chromene-2-carboxylic acid derivative and intermediates preparation thereof | SANWA KAGAKU KENKYUSHO K K (JP) | 1989-09-27 | — | — | CN | disclosed |
| EP-0331078-A2 | Process for the preparation of optically active 4-oxo-1-benzopyran-2-carboxylic acid derivatives and intermediates thereof | SANWA KAGAKU KENKYUSHO CO., LTD. (JP) | 1989-09-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10322122-B2 | Methods and compositions for treating degenerative and ischemic disorders | PINK1, PC, PCK2 | IDO1 1083/4885TDO2 2057/4885ADRB2 1359/4885 |
| US-20090221823-A1 | OPTICALLY ACTIVE CARBAMATES, PROCESS FOR PREPARATION THEREOF AND USE THEREOF AS PHARMACEUTICAL INTERMEDIATES | HRH4, HRH1, HRH2 | IDO1 400/4885TDO2 710/4885ADRB2 457/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.