SCHEMBL5884635

SCHEMBL5884635

C=CCNC(=O)c1ccc(O)cc1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 6/20 0.67
LMNA P02545 2/20 0.67
ALDH1A1 P00352 2/20 0.67
SMN1; SMN2 Q16637 4/20 0.66
PKM P14618 2/20 0.65
RAB9A P51151 3/20 0.61
MEN1 O00255 1/20 0.55
KMT2A Q03164 1/20 0.55
MAPT P10636 3/20 0.54
MPO P05164 1/20 0.53
CYP3A4 P08684 1/20 0.53
KDM5A P29375 1/20 0.53
BLM P54132 1/20 0.53
GFER P55789 1/20 0.53
PMP22 Q01453 1/20 0.53
HIF1A Q16665 1/20 0.53
POLB P06746 1/20 0.53
CA1 P00915 1/20 0.50
GAA P10253 1/20 0.50
CA9 Q16790 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2385213 0.92 HPGD (0.76) HPGDLMNAALDH1A1SMN1; SMN2PKM
SCHEMBL8557641 0.83 LMNA (0.65) HPGDLMNAALDH1A1SMN1; SMN2PKM
SCHEMBL28804019 0.83 SMN1; SMN2 (0.69) HPGDLMNAALDH1A1SMN1; SMN2PKM
SCHEMBL17426922 0.83 HPGD (0.65) HPGDLMNAALDH1A1SMN1; SMN2PKM
SCHEMBL13397394 0.83 HPGD (0.65) HPGDLMNAALDH1A1SMN1; SMN2PKM
SCHEMBL24227389 0.83 RAB9A (0.69) HPGDLMNAALDH1A1SMN1; SMN2PKM
SCHEMBL17426921 0.83 HPGD (0.65) HPGDLMNAALDH1A1SMN1; SMN2PKM
SCHEMBL9068167 0.83 PKM (0.68) HPGDLMNAALDH1A1SMN1; SMN2PKM
SCHEMBL17426924 0.83 HPGD (0.65) HPGDLMNAALDH1A1SMN1; SMN2PKM
SCHEMBL7105506 0.83 HPGD (0.65) HPGDLMNAALDH1A1SMN1; SMN2PKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104995289-B Lubricant compositions comprising 4-hydroxybenzamide friction modifiers 路博润公司 2020-12-22 CN claimed
EP-2935540-B1 LUBRICANT COMPOSITION INCLUDING 4-HYDROXYBENZAMIDE FRICTION MODIFIER LUBRIZOL CORP (US) 2019-10-16 EP claimed
US-9765274-B2 Lubricant composition including 4-hydroxybenzamide friction modifier THE LUBRIZOL CORPORATION (US) 2017-09-19 US claimed
US-20160024413-A1 LUBRICANT COMPOSITION INCLUDING 4-HYDROXYBENZAMIDE FRICTION MODIFIER THE LUBRIZOL CORPORATION (US) 2016-01-28 US claimed
EP-2935540-A1 LUBRICANT COMPOSITION INCLUDING 4-HYDROXYBENZAMIDE FRICTION MODIFIER The Lubrizol Corporation (US) 2015-10-28 EP claimed
CN-104995289-A Lubricant composition including 4-hydroxybenzamide friction modifier LUBRIZOL CORP 2015-10-21 CN claimed
WO-2014099537-A1 LUBRICANT COMPOSITION INCLUDING 4-HYDROXYBENZAMIDE FRICTION MODIFIER THE LUBRIZOL CORPORATION (US) 2014-06-26 WO claimed
CN-104995289-B Lubricant compositions comprising 4-hydroxybenzamide friction modifiers 路博润公司 2020-12-22 CN disclosed
EP-2935540-B1 LUBRICANT COMPOSITION INCLUDING 4-HYDROXYBENZAMIDE FRICTION MODIFIER LUBRIZOL CORP (US) 2019-10-16 EP disclosed
US-9765274-B2 Lubricant composition including 4-hydroxybenzamide friction modifier THE LUBRIZOL CORPORATION (US) 2017-09-19 US disclosed
US-20160024413-A1 LUBRICANT COMPOSITION INCLUDING 4-HYDROXYBENZAMIDE FRICTION MODIFIER THE LUBRIZOL CORPORATION (US) 2016-01-28 US disclosed
EP-2935540-A1 LUBRICANT COMPOSITION INCLUDING 4-HYDROXYBENZAMIDE FRICTION MODIFIER The Lubrizol Corporation (US) 2015-10-28 EP disclosed
CN-104995289-A Lubricant composition including 4-hydroxybenzamide friction modifier LUBRIZOL CORP 2015-10-21 CN disclosed
US-6184180-B1 COMPRISES SUPPORT, REVERSIBLE HEAT-SENSITIVE RECORDING LAYER CONTAINING DYE PRECURSOR WHICH IS COLORLESS OR A PALE COLOR, COLOR DEVELOPER CAPABLE OF CAUSING REVERSIBLE CHANGE IN COLOR DENSITY OF DYE DUE TO DIFFERENCE IN COOLING RATE MITSUBISHI PAPER MILLS LIMITED (JP) 2001-02-06 US disclosed
EP-0999071-A2 Reversible heat-sensitive paper and methods for writing information Riken (JP) 2000-05-10 EP disclosed
US-6004899-A SURFACE TREATED WITH SILANE, TITANATE, AND/OR ALUMINUM COUPLING AGENT; PIGMENT; ERASIBILITY MITSUBISHI PAPER MILLS LIMITED (JP) 1999-12-21 US disclosed
US-5817599-A COLORLESS DYE PRECURSOR AND REVERSIBLE COLOR DEVELOPER MITSUBISHI PAPER MILLS LIMITED (JP) 1998-10-06 US disclosed
EP-0648612-B1 Reversible heat-sensitive recording material MITSUBISHI PAPER MILLS LTD (JP) 1998-06-10 EP disclosed
US-5498772-A SUBSTRATE WITH HEAT SENSITIVE LAYER AND OPTICAL RECORDING LAYER MITSUBISHI PAPER MILLS LIMITED (JP) 1996-03-12 US disclosed
EP-0648612-A1 Reversible heat-sensitive recording material MITSUBISHI PAPER MILLS, LTD. (JP) 1995-04-19 EP disclosed