Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 2/20 | 0.68 |
| ▸ | HPGD | P15428 | 5/20 | 0.65 |
| ▸ | LMNA | P02545 | 3/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.64 |
| ▸ | RAB9A | P51151 | 5/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 4/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.52 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2385213 | 0.90 | HPGD (0.76) | PKMHPGDLMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL3993032 | 0.83 | LMNA (0.62) | HPGDLMNAALDH1A1SMN1; SMN2RAB9A | |
| SCHEMBL7208359 | 0.83 | POLB (0.58) | PKMHPGDLMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL5884635 | 0.83 | HPGD (0.67) | PKMHPGDLMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL11952641 | 0.82 | PKM (0.64) | PKMHPGDLMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL22251000 | 0.82 | PKM (0.64) | PKMHPGDLMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL24227389 | 0.81 | RAB9A (0.69) | PKMHPGDLMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL13397394 | 0.81 | HPGD (0.65) | PKMHPGDLMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL17426921 | 0.81 | HPGD (0.65) | PKMHPGDLMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL7105506 | 0.81 | HPGD (0.65) | PKMHPGDLMNAALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5534174-A | LUBRICANT ADDITIVE, DISPERSANT, VISCOSITY INDEX IMPROVER | ETHYL PETROLEUM ADDITIVES, INC. (US) | 1996-07-09 | — | — | US | claimed |
| CN-116813471-A | Trifluoromethyl alkynylation reaction of photocatalytic 1, 6-diene and application | 郑州大学 | 2023-09-29 | — | — | CN | disclosed |
| US-9078902-B2 | Triazine derivatives and their therapeutical applications | NANTBIOSCIENCE, INC. (US) | 2015-07-14 | — | — | US | disclosed |
| EP-1802636-B1 | PI3 KINASES INHIBITORS | BOEHRINGER INGELHEIM INT (DE) | 2013-03-27 | — | — | EP | disclosed |
| WO-2010144550-A1 | TRIAZINE DERIVATIVES AND THEIR THERAPEUTICAL APPLICATIONS | ABRAXIS BIOSCIENCE, LLC (US) | 2010-12-16 | — | — | WO | disclosed |
| US-20090029990-A1 | Dihydropteridinones in the treatment of respiratory diseases | MAIER UDO | 2009-01-29 | — | — | US | disclosed |
| US-20070066513-A1 | Substituted metal-phthalocyanines, their preparation and the use thereof | MOLTENI THERAPEUTICS S.R.L. (IT) | 2007-03-22 | — | — | US | disclosed |
| US-20070043055-A1 | Dihydropteridinones in the treatment of respiratory diseases | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2007-02-22 | — | — | US | disclosed |
| US-5534174-A | LUBRICANT ADDITIVE, DISPERSANT, VISCOSITY INDEX IMPROVER | ETHYL PETROLEUM ADDITIVES, INC. (US) | 1996-07-09 | — | — | US | disclosed |
| EP-0087234-B1 | ASHLESS DISPERSANT COMPOUNDS, THEIR PREPARATION, AND THEIR USE IN PROVIDING DISPERSANCY IN LUBRICATING OILS OR LIQUID FUELS | EDWIN COOPER INC. (US) | 1986-11-12 | — | — | EP | disclosed |
| US-4519929-A | ASHLESS DISPERSANTS; OIL AND FUEL ADDITIVES | EDWIN COOPER, INC. (US) | 1985-05-28 | — | — | US | disclosed |
| EP-0087234-A1 | Ashless dispersant compounds, their preparation, and their use in providing dispersancy in lubricating oils or liquid fuels | EDWIN COOPER INC. (US) | 1983-08-31 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070066513-A1 | Substituted metal-phthalocyanines, their preparation and the use thereof | CD47, CD99, MEN1 | PKM 212/4885HPGD 2736/4885LMNA 517/4885 |
| US-20070043055-A1 | Dihydropteridinones in the treatment of respiratory diseases | QDPR, DHPS, NDUFS6 | PKM 2731/4885HPGD 59/4885LMNA 2051/4885 |
| US-20090029990-A1 | Dihydropteridinones in the treatment of respiratory diseases | QDPR, DHPS, NDUFS6 | PKM 2731/4885HPGD 59/4885LMNA 2051/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.