SCHEMBL5885199

SCHEMBL5885199

ClCc1ccc(CCl)c2cc3c(CCl)ccc(CCl)c3cc12

nearest known ligand 0.35

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.35
KMT2A Q03164 2/20 0.33
MCL1 Q07820 2/20 0.31
PON1 P27169 1/20 0.31
ALDH1A1 P00352 1/20 0.31
TSHR P16473 1/20 0.31
NPSR1 Q6W5P4 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29558862 0.78 L3MBTL1 (0.44) L3MBTL1KMT2AALDH1A1TSHR
SCHEMBL2466440 0.78 L3MBTL1 (0.44) L3MBTL1KMT2AALDH1A1TSHR
SCHEMBL11319615 0.73 KMT2A (0.30) KMT2A
SCHEMBL1561687 0.71 CYP2A6 (0.35) L3MBTL1ALDH1A1TSHR
SCHEMBL2468219 0.71 ALDH1A1 (0.39) L3MBTL1KMT2AALDH1A1TSHR
SCHEMBL29383544 0.71 ALDH1A1 (0.39) L3MBTL1KMT2AALDH1A1TSHR
SCHEMBL3403920 0.70 KMT2A (0.33) KMT2AMCL1ALDH1A1TSHRNPSR1
SCHEMBL29208988 0.69 ALDH1A1 (0.34) L3MBTL1KMT2AALDH1A1TSHR
SCHEMBL11022982 0.69 PYCR1 (0.43) L3MBTL1KMT2AALDH1A1TSHR
SCHEMBL9016045 0.69 KMT2A (0.34) KMT2AALDH1A1TSHRNPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7030171-B2 Process for producing vinyl polymer having functional group at end and vinyl polymer having functional group at end SEKISUI CHEMICAL CO., LTD. (JP) 2006-04-18 US disclosed
US-20040092619-A1 Process for producing vinyl polymer having functional group at end and vinyl polymer having functional group at end WAKIYA TAKESHI (JP) 2004-05-13 US disclosed
US-6693142-B1 POLYMERIZATION REACTION OF VINYL MONOMERS IN PRESENCE OF HALOGEN COMPOUND AND SUBSTITUTING WITH SUCH AS HYDROXYL, AMINO, VINYL OR SILYL GROUPS SEKISUI CHEMICAL CO., LTD. (JP) 2004-02-17 US disclosed
EP-1243599-A1 PROCESS FOR PRODUCING VINYL POLYMER HAVING FUNCTIONAL GROUP AT END AND VINYL POLYMER HAVING FUNCTIONAL GROUP AT END SEKISUI CHEMICAL CO., LTD. (JP) 2002-09-25 EP disclosed