Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.36 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.34 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.34 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | MAPT | P10636 | 4/20 | 0.32 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | THRB | P10828 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | SYK | P43405 | 2/20 | 0.32 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.32 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.32 |
| ▸ | RORC | P51449 | 1/20 | 0.32 |
| ▸ | SMPD3 | Q9NY59 | 2/20 | 0.31 |
| ▸ | HTT | P42858 | 3/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.30 |
| ▸ | GFER | P55789 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5885737 | 0.94 | AR (0.35) | GAAALDH1A1MAPTKMT2ASYK | |
| SCHEMBL5885629 | 0.87 | GAA (0.35) | GAAALDH1A1MAPTMEN1THRB | |
| SCHEMBL5885250 | 0.87 | RORC (0.39) | GAASMARCA2SMARCA4PBRM1ALDH1A1 | |
| SCHEMBL5884862 | 0.87 | MAPT (0.42) | GAALMNAALDH1A1MAPTMEN1 | |
| SCHEMBL5884854 | 0.86 | KDM4E (0.41) | GAAALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL5884912 | 0.86 | SMPD3 (0.33) | LMNASYKRORCSMPD3 | |
| SCHEMBL5885575 | 0.86 | MAPT (0.44) | GAALMNAALDH1A1MAPTMEN1 | |
| SCHEMBL5885723 | 0.84 | ALDH1A1 (0.34) | GAAALDH1A1MAPTKMT2ASYK | |
| SCHEMBL5884843 | 0.80 | RORC (0.37) | RORC | |
| SCHEMBL5884801 | 0.79 | ADRB1 (0.38) | GAALMNAALDH1A1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7101406-B2 | Dyeing composition comprising a cationic tertiary para-phenylenediamine and a heterocyclic cationic direct dye, methods and uses | L'OREAL (FR) | 2006-09-05 | — | — | US | claimed |
| US-6824570-B2 | CHROMATIC DIRECT DYES OF 2-AZO BENZIMIDAZOLE, BENZOTHIAZOLE OR BENZOXAOZLE DERIVATIVES | L'OREAL S.A. (FR) | 2004-11-30 | — | — | US | claimed |
| US-20040221399-A1 | Dyeing composition comprising a cationic tertiary para-phenylenediamine and a heterocyclic cationic direct dye, methods and uses | L'OREAL (FR) | 2004-11-11 | — | — | US | claimed |
| EP-1428505-A1 | Dyeing composition comprising a tertiary paraphenylenediamine containing a pyrrolidine, and a cationic direct dye containing a heterocyclic group ; method and use | L'OREAL (FR) | 2004-06-16 | — | — | EP | claimed |
| US-20030106169-A1 | Composition for dyeing human keratin fibres, comprising a particular monocationic monoazo dye | L'OREAL S.A. (FR) | 2003-06-12 | — | — | US | claimed |
| CN-1410047-A | Composition containing specific single cation monoazo dye for dyeing human cutin fiber | OREAL (FR) | 2003-04-16 | — | — | CN | claimed |
| EP-1297819-A2 | Composition for dyeing keratinous fibres comprising a cationic azo dye | L'OREAL (FR) | 2003-04-02 | — | — | EP | claimed |
| US-7101406-B2 | Dyeing composition comprising a cationic tertiary para-phenylenediamine and a heterocyclic cationic direct dye, methods and uses | L'OREAL (FR) | 2006-09-05 | — | — | US | disclosed |
| US-20060112502-A1 | Dyeing composition comprising a cationic tertiary para-phenylenediamine and a heterocyclic cationic direct dye, methods and uses | L'OREAL (FR) | 2006-06-01 | — | — | US | disclosed |
| CN-1245150-C | Composition containing specific single cation monoazo dye for dyeing human cutin fiber | OREAL (FR) | 2006-03-15 | — | — | CN | disclosed |
| US-6824570-B2 | CHROMATIC DIRECT DYES OF 2-AZO BENZIMIDAZOLE, BENZOTHIAZOLE OR BENZOXAOZLE DERIVATIVES | L'OREAL S.A. (FR) | 2004-11-30 | — | — | US | disclosed |
| US-20040221399-A1 | Dyeing composition comprising a cationic tertiary para-phenylenediamine and a heterocyclic cationic direct dye, methods and uses | L'OREAL (FR) | 2004-11-11 | — | — | US | disclosed |
| EP-1428505-A1 | Dyeing composition comprising a tertiary paraphenylenediamine containing a pyrrolidine, and a cationic direct dye containing a heterocyclic group ; method and use | L'OREAL (FR) | 2004-06-16 | — | — | EP | disclosed |
| US-20030106169-A1 | Composition for dyeing human keratin fibres, comprising a particular monocationic monoazo dye | L'OREAL S.A. (FR) | 2003-06-12 | — | — | US | disclosed |
| CN-1410047-A | Composition containing specific single cation monoazo dye for dyeing human cutin fiber | OREAL (FR) | 2003-04-16 | — | — | CN | disclosed |
| EP-1297819-A2 | Composition for dyeing keratinous fibres comprising a cationic azo dye | L'OREAL (FR) | 2003-04-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030106169-A1 | Composition for dyeing human keratin fibres, comprising a particular monocationic monoazo dye | KRT18, TUBB3, TUBB1 | GAA 4564/4885SMARCA2 2302/4885SMARCA4 2568/4885 |
| US-20060112502-A1 | Dyeing composition comprising a cationic tertiary para-phenylenediamine and a heterocyclic cationic direct dye, methods and uses | KRT18, CDC73, NUP205 | GAA 4728/4885SMARCA2 4642/4885SMARCA4 4364/4885 |
| US-20040221399-A1 | Dyeing composition comprising a cationic tertiary para-phenylenediamine and a heterocyclic cationic direct dye, methods and uses | KRT18, CDC73, NUP205 | GAA 4728/4885SMARCA2 4642/4885SMARCA4 4364/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.