Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 5/20 | 0.53 |
| ▸ | LMNA | P02545 | 5/20 | 0.53 |
| ▸ | SHBG | P04278 | 4/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 4/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.53 |
| ▸ | SERPINA6 | P08185 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | BLM | P54132 | 2/20 | 0.53 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.53 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.53 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.53 |
| ▸ | PGR | P06401 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.49 |
| ▸ | HTR2B | P41595 | 1/20 | 0.49 |
| ▸ | AR | P10275 | 3/20 | 0.48 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Haloprogesterone SCHEMBL139523 | 0.85 | AR (0.64) | NR3C1LMNASHBGCYP2C19MEN1 | |
| Haloprogesterone SCHEMBL139522 | 0.85 | AR (0.64) | NR3C1LMNASHBGCYP2C19MEN1 | |
| SCHEMBL148415 | 0.84 | SHBG (0.69) | NR3C1LMNASHBGCYP2C19MEN1 | |
| SCHEMBL10867348 | 0.84 | SHBG (0.69) | NR3C1LMNASHBGCYP2C19MEN1 | |
| SCHEMBL10867342 | 0.84 | SHBG (0.69) | NR3C1LMNASHBGCYP2C19MEN1 | |
| SCHEMBL3136318 | 0.81 | LMNA (0.73) | NR3C1LMNASHBGCYP2C19MEN1 | |
| SCHEMBL11510735 | 0.75 | LMNA (0.78) | NR3C1LMNASHBGCYP2C19MEN1 | |
| SCHEMBL11510737 | 0.75 | LMNA (0.78) | NR3C1LMNASHBGCYP2C19MEN1 | |
| SCHEMBL15079258 | 0.73 | LMNA (0.49) | NR3C1LMNASHBGCYP2C19MEN1 | |
| SCHEMBL15079253 | 0.73 | LMNA (0.49) | NR3C1LMNASHBGCYP2C19MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7026360-B1 | Pharmaceutical compositions containing compounds with activity for the enhancement of absorption of active ingredients | INPHARMA S.A. (CH) | 2006-04-11 | — | — | US | disclosed |