Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Sulfachrysoidine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | USP2 | O75604 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 6/20 | 0.38 |
| ▸ | CA1 | P00915 | 5/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.38 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.38 |
| ▸ | SLCO2B1 | O94956 | 1/20 | 0.38 |
| ▸ | MMP1 | P03956 | 1/20 | 0.38 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfacytine SCHEMBL28251252 | 0.81 | CA1 (0.48) | MAPTUSP2TDP1CA2CA1 | |
| Sulfacytine SCHEMBL49377 | 0.77 | HTR6 (0.50) | MAPTTDP1ALDH1A1CYP2C9LMNA | |
| Sulfachrysoidine SCHEMBL49739 | 0.76 | PTGS2 (0.60) | MAPTMEN1KMT2AUSP2POLB | |
| Sulfachrysoidine SCHEMBL49738 | 0.76 | PTGS2 (0.60) | MAPTMEN1KMT2AUSP2POLB | |
| SCHEMBL17471609 | 0.72 | MEN1 (0.44) | MAPTMEN1KMT2AUSP2POLB | |
| Sulfacytine SCHEMBL28122249 | 0.71 | LMNA (0.60) | MAPTMEN1KMT2ATDP1ALDH1A1 | |
| SCHEMBL11925227 | 0.70 | PTPN11 (0.50) | MAPTMEN1KMT2AUSP2POLB | |
| SCHEMBL10697070 | 0.69 | KDM4E (0.51) | MAPTMEN1KMT2AUSP2POLB | |
| Sulfasalazine SCHEMBL3226246 | 0.65 | SLC7A11 (0.85) | MAPTMEN1KMT2AUSP2CA2 | |
| SCHEMBL31634616 | 0.63 | KMT2A (0.54) | MAPTMEN1KMT2AUSP2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7026360-B1 | Pharmaceutical compositions containing compounds with activity for the enhancement of absorption of active ingredients | INPHARMA S.A. (CH) | 2006-04-11 | — | — | US | disclosed |