Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 2/20 | 0.42 |
| ▸ | GLO1 | Q04760 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | CASP1 | P29466 | 2/20 | 0.40 |
| ▸ | CASP7 | P55210 | 2/20 | 0.40 |
| ▸ | GLA | P06280 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | TOP2A | P11388 | 2/20 | 0.39 |
| ▸ | TOP2B | Q02880 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.39 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.39 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | TOP1 | P11387 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17187705 | 0.77 | GLO1 (0.57) | KDM1AGLO1CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL5886403 | 0.77 | ALDH1A1 (0.46) | KDM1ACYP1A2CYP2D6CYP2C9CASP1 | |
| Phenazine SCHEMBL1750964 | 0.65 | MAPT (0.58) | KDM1ACYP1A2CYP2D6CYP2C9CASP1 | |
| SCHEMBL21489525 | 0.65 | GLO1 (0.59) | GLO1GLATP53RAB9ATSHR | |
| SCHEMBL11209338 | 0.64 | NQO2 (0.45) | CYP1A2CYP2C9RAB9ATSHRALDH1A1 | |
| SCHEMBL10786542 | 0.64 | ELANE (0.43) | KDM1ARAB9AALDH1A1KDM4EHPGD | |
| Sulfuric Acid SCHEMBL28762472 | 0.64 | ALDH1A1 (0.41) | CYP1A2CYP2D6CYP2C9CASP1CASP7 | |
| SCHEMBL31607195 | 0.63 | ALDH1A1 (0.48) | CYP1A2RAB9AHSD17B10CYP3A4TSHR | |
| SCHEMBL2068498 | 0.63 | KEAP1 (0.65) | GLO1HSD17B10TSHRPTGS2ALDH1A1 | |
| SCHEMBL29904739 | 0.63 | KEAP1 (0.65) | GLO1HSD17B10TSHRPTGS2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7132419-B2 | Pharmaceutical compounds | XENOVA LIMITED (GB) | 2006-11-07 | — | — | US | disclosed |
| US-20050143383-A1 | Pharmaceutical compounds | XENOVA LIMITED (GB) | 2005-06-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050143383-A1 | Pharmaceutical compounds | CHRNA10, OPRM1, SCN10A | KDM1A 3135/4885GLO1 4318/4885CYP1A2 184/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.