Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | PTGER4 | P35408 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
| ▸ | OGFRL1 | Q5TC84 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | MMP13 | P45452 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5887234 | 0.97 | HDAC1 (0.42) | HDAC1LMNAHPGDALOX12SMN1; SMN2 | |
| SCHEMBL5887537 | 0.94 | ALDH1A1 (0.41) | HDAC1LMNAHPGDALOX12SMN1; SMN2 | |
| SCHEMBL5887359 | 0.93 | MAOA (0.41) | HDAC1LMNAHPGDALOX12SMN1; SMN2 | |
| SCHEMBL5887193 | 0.90 | SMN1; SMN2 (0.43) | LMNASMN1; SMN2TP53MAPTALDH1A1 | |
| SCHEMBL5887463 | 0.87 | LMNA (0.45) | HDAC1LMNASMN1; SMN2TP53OPRK1 | |
| SCHEMBL5887380 | 0.87 | PPARG (0.41) | HDAC1LMNATP53ALDH1A1MEN1 | |
| SCHEMBL5887284 | 0.86 | MAPT (0.40) | HDAC1LMNATP53MAPTDCTPP1 | |
| SCHEMBL5887531 | 0.86 | HDAC1 (0.42) | HDAC1LTA4HOPRM1OPRK1 | |
| SCHEMBL5887173 | 0.80 | LMNA (0.39) | LMNAL3MBTL1PTGER4TP53MAPT | |
| SCHEMBL5887418 | 0.80 | LMNA (0.39) | LMNAL3MBTL1TP53MAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7019002-B2 | Substituted on 8th position with benzoic acid, ester or amide groups; anticancer agents | PHARMACIA & UPJOHN, S.P.A. (IT) | 2006-03-28 | — | — | US | disclosed |