SCHEMBL58872

SCHEMBL58872

[CH2]CCCc1ccccc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 4/20 0.54
MAOA P21397 1/20 0.54
MAOB P27338 2/20 0.52
HTR2A P28223 1/20 0.52
HTR3A P46098 1/20 0.52
IDO1 P14902 1/20 0.50
HDAC3 O15379 1/20 0.50
MAPK1 P28482 1/20 0.50
ADRA1A P35348 1/20 0.50
HDAC4 P56524 1/20 0.50
SLC6A3 Q01959 1/20 0.50
HDAC1 Q13547 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.50
HDAC7 Q8WUI4 1/20 0.50
HDAC2 Q92769 1/20 0.50
HDAC10 Q969S8 1/20 0.50
HDAC11 Q96DB2 1/20 0.50
HDAC8 Q9BY41 1/20 0.50
HDAC6 Q9UBN7 1/20 0.50
HDAC9 Q9UKV0 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22129856 0.97 SIGMAR1 (0.52) SIGMAR1MAOAMAOBHTR2AHTR3A
SCHEMBL4654157 0.97 SIGMAR1 (0.52) SIGMAR1MAOAMAOBHTR2AHTR3A
SCHEMBL58873 0.92 MAOA (0.58) SIGMAR1MAOAMAOBHTR2AHTR3A
SCHEMBL8498459 0.90 SIGMAR1 (0.58) SIGMAR1MAOAMAOBL3MBTL1
SCHEMBL20918479 0.90 MAOA (0.56) SIGMAR1MAOAMAOBHTR2AHTR3A
SCHEMBL145792 0.90 SIGMAR1 (0.58) SIGMAR1MAOAMAOBL3MBTL1
SCHEMBL104035 0.90 SIGMAR1 (0.58) SIGMAR1MAOAMAOBL3MBTL1
SCHEMBL304117 0.90 SIGMAR1 (0.58) SIGMAR1MAOAMAOBL3MBTL1
SCHEMBL8497063 0.90 SIGMAR1 (0.58) SIGMAR1MAOAMAOBL3MBTL1
SCHEMBL8496868 0.90 SIGMAR1 (0.58) SIGMAR1MAOAMAOBL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 25301 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4121802-B1 HIGH REFRACTIVE INDEX SILOXANE INSERT MATERIALS FOR EMBEDDED CONTACT LENSES ALCON INC (CH) 2024-07-17 EP claimed
WO-2024140062-A1 THIOXANTHENIUM SALT PHOTOINITIATOR, AND PREPARATION METHOD THEREFOR AND USE THEREOF 常州强力电子新材料股份有限公司 2024-07-04 WO claimed
WO-2024140063-A1 THIOXANTHENE SULFONIUM SALT PHOTOINITIATOR AS WELL AS PREPARATION METHOD THEREFOR AND USE THEREOF 常州强力电子新材料股份有限公司 2024-07-04 WO claimed
CN-118271281-A Thioxanthene sulfonium salt photoinitiator and preparation method and application thereof 常州强力电子新材料股份有限公司 2024-07-02 CN claimed
CN-118271280-A Thioxanthene sulfonium salt photoinitiator and preparation method and application thereof 常州强力电子新材料股份有限公司 2024-07-02 CN claimed
CN-116355009-B Organometallic complex, catalyst composition comprising the same, and process for producing polyolefin 财团法人工业技术研究院 2024-06-28 CN claimed
US-20240207253-A1 Inhibitors of CDR1 for Reversal of Azole Drug Resistance in Fungal Infections THE UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS 2024-06-27 US claimed
CN-118146196-A FAP inhibitors 海德堡大学 2024-06-07 CN claimed
WO-2024104384-A1 INDENE COMPOUNDS, PHARMACEUTICAL COMPOSITIONS THEREOF, AND THEIR THERAPEUTIC APPLICATIONS NUCMITO PHARMACEUTICALS CO. LTD. (CN) 2024-05-23 WO claimed
US-11958923-B2 Compositions with high refractive index and abbe number Johnson & Johnson Surgical Vision, Inc. (US) 2024-04-16 US claimed
US-4169152-A Isohexide and tetrahydrofuran ethers and their carbamates in method of bringing about relaxation of skeletal musculature ICI AMERICAS INC. (US) 1979-09-25 US claimed
US-4130583-A AUTOGENOUS PRESSURE STAUFFER CHEMICAL COMPANY (US) 1978-12-19 US claimed
US-4119726-A ANTISECRETORY AGENTS, BRONCHODILATORS, ANTICOAGULANTS BEECHAM GROUP LIMITED (GB) 1978-10-10 US claimed
US-4060522-A ANTICORROSIVE BASF AKTIENGESELLSCHAFT (DT) 1977-11-29 US claimed
US-4052463-A PROCESS FOR PREPARING TERTIARY PHOSPHINE SULFIDES AND OXIDES STAUFFER CHEMICAL COMPANY (US) 1977-10-04 US claimed
US-4046572-A SILVER HALIDE PHOTOGRAPHIC LIGHT SENSITIVE MATERIAL FUJI PHOTO FILM CO., LTD. (JA) 1977-09-06 US claimed
US-4000190-A FROM DIALKYL OR DIARYL DISULFIDES, PHOSPHORUS, AND PHOSPHORUS TRIHALIDE STAUFFER CHEMICAL COMPANY (US) 1976-12-28 US claimed
US-3968156-A Process for preparing alkyl-or arylphosphonothioic dihalides STAUFFER CHEMICAL COMPANY (US) 1976-07-06 US claimed
US-3962323-A PHOSPHORUS TRIHALIDE STAUFFER CHEMICAL COMPANY (US) 1976-06-08 US claimed
US-3956177-A Rhodium hydroformylation catalyst PHILLIPS PETROLEUM COMPANY (US) 1976-05-11 US claimed