Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 4/20 | 0.32 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5887667 | 0.89 | NPC1 (0.39) | MEN1KMT2AMAPTNR1H4TP53 | |
| SCHEMBL5887426 | 0.86 | MEN1 (0.34) | MEN1KMT2APOLBTP53 | |
| SCHEMBL5887191 | 0.86 | MEN1 (0.37) | MEN1KMT2APOLBMAPTHTR2C | |
| SCHEMBL6047617 | 0.82 | TUBB4A (0.37) | MEN1KMT2APOLBMAPTTP53 | |
| SCHEMBL5887353 | 0.81 | MEN1 (0.35) | MEN1KMT2AHTR2CTP53 | |
| SCHEMBL5887287 | 0.78 | ACHE (0.46) | MEN1KMT2AMAPT | |
| SCHEMBL5887105 | 0.77 | ESR2 (0.35) | POLBMAPTTP53 | |
| SCHEMBL6047646 | 0.77 | CYP2D6 (0.32) | — | |
| SCHEMBL5887653 | 0.76 | FFAR2 (0.40) | KMT2AMAPT | |
| SCHEMBL5887589 | 0.75 | APEX1 (0.36) | MAPTHTR2CTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7037931-B2 | Corticotropin releasing factor moderator; analgesics; drug abruse, drug dependency; schizophrenia | JANSSEN PHARMACEUTICA N.V. (BE) | 2006-05-02 | — | — | US | claimed |
| JP-2006501194-A | — | — | 2006-01-12 | — | — | JP | claimed |
| EP-1525190-A1 | CCK-1 RECEPTOR MODULATORS | JANSSEN PHARMACEUTICA N.V. (BE) | 2005-04-27 | — | — | EP | claimed |
| WO-2004007463-A1 | CCK-1 RECEPTOR MODULATORS | JANSSEN PHARMACEUTICA, N.V. (BE) | 2004-01-22 | — | — | WO | claimed |