Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B2 | P37059 | 7/20 | 0.46 |
| ▸ | HSD17B1 | P14061 | 6/20 | 0.46 |
| ▸ | FYN | P06241 | 4/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.38 |
| ▸ | APP | P05067 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL323109 | 0.84 | DYRK1A (0.49) | NOTUM | |
| SCHEMBL8063028 | 0.83 | APP (0.49) | APP | |
| SCHEMBL16719334 | 0.80 | NFE2L2 (0.46) | — | |
| SCHEMBL7033071 | 0.79 | CA4 (0.43) | — | |
| SCHEMBL4288060 | 0.78 | HSD17B1 (0.44) | HSD17B2HSD17B1FYN | |
| SCHEMBL7101700 | 0.78 | MAOB (0.42) | — | |
| SCHEMBL10887641 | 0.76 | APP (0.46) | APP | |
| SCHEMBL9509841 | 0.76 | TLR9 (0.42) | HSD17B2HSD17B1APP | |
| SCHEMBL10918406 | 0.76 | CYP11B1 (0.44) | — | |
| SCHEMBL11233784 | 0.76 | ALDH1A1 (0.46) | FYNNOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7037931-B2 | Corticotropin releasing factor moderator; analgesics; drug abruse, drug dependency; schizophrenia | JANSSEN PHARMACEUTICA N.V. (BE) | 2006-05-02 | — | — | US | claimed |