Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.41 |
| ▸ | BRD7 | Q9NPI1 | 1/20 | 0.41 |
| ▸ | HTR7 | P34969 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 5/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3281142 | 0.80 | RAB9A (0.46) | HTR7ACHEMAPTMEN1KMT2A | |
| SCHEMBL5887422 | 0.77 | HTR7 (0.42) | HTR7SLC6A2SLC6A4SLC6A3MAPT | |
| SCHEMBL8617214 | 0.76 | BRD9 (0.46) | BRD9BRD7ACHEMAPTMEN1 | |
| SCHEMBL11079208 | 0.75 | HTR7 (0.44) | BRD9BRD7HTR7ACHENPC1 | |
| SCHEMBL27414909 | 0.75 | CA12 (0.46) | BRD9BRD7MAPTTP53HPGD | |
| SCHEMBL1782448 | 0.74 | HTR7 (0.50) | HTR7MAPTHPGDLMNAHSD17B10 | |
| SCHEMBL726663 | 0.74 | MEN1 (0.39) | SLC6A2SLC6A4SLC6A3ACHEMAPT | |
| Hydrogen Sulfide SCHEMBL27964903 | 0.73 | CA12 (0.45) | BRD9BRD7MAPTTP53HPGD | |
| SCHEMBL26841190 | 0.72 | HTR7 (0.46) | HTR7HPGDHSD17B10ALDH1A1NPC1 | |
| SCHEMBL8674981 | 0.71 | ALDH1A1 (0.56) | BRD9BRD7MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7112697-B1 | Methods for formation of aryl-sulfur and aryl-selenium compounds using copper(I) catalysts | UNIVERSITY OF MASSACHUSETTS (US) | 2006-09-26 | — | — | US | disclosed |
| CN-1684944-A | method for copper-catalyzed formation of carbon-heteroatom and carbon-carbon bonds | MASSACHUSETTS INST TECHNOLOGY (US) | 2005-10-19 | — | — | CN | disclosed |