Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORB | Q92753 | 1/20 | 0.36 |
| ▸ | TDO2 | P48775 | 1/20 | 0.36 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.34 |
| ▸ | NUDT1 | P36639 | 3/20 | 0.33 |
| ▸ | KMO | O15229 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 2/20 | 0.33 |
| ▸ | PIM1 | P11309 | 1/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.32 |
| ▸ | FYN | P06241 | 1/20 | 0.32 |
| ▸ | PLK1 | P53350 | 1/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.32 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.32 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.32 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.32 |
| ▸ | HRH1 | P35367 | 1/20 | 0.32 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.31 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4009271 | 0.76 | — | — | |
| SCHEMBL4145649 | 0.73 | ALOX5 (0.38) | IDO1NOTUMCHRNB4CHRNA3 | |
| SCHEMBL6047657 | 0.67 | NOTUM (0.39) | NOTUMPDE10A | |
| SCHEMBL27653332 | 0.63 | KDM4E (0.42) | TDO2IDO1ADORA2AADORA1 | |
| SCHEMBL29796567 | 0.63 | RORB (0.63) | RORBTDO2IDO1NOTUMADORA2A | |
| SCHEMBL18447962 | 0.61 | RORB (0.49) | RORBTDO2MAP4K4NUDT1KMO | |
| SCHEMBL6047598 | 0.60 | HTR2C (0.39) | IDO1NOTUMCHRNB4CHRNA3 | |
| SCHEMBL4453356 | 0.60 | ALOX5 (0.44) | IDO1NOTUM | |
| SCHEMBL30387433 | 0.60 | ALOX5 (0.44) | IDO1NOTUM | |
| SCHEMBL18483443 | 0.59 | ADORA2A (0.50) | RORBTDO2MAP4K4IDO1ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7037931-B2 | Corticotropin releasing factor moderator; analgesics; drug abruse, drug dependency; schizophrenia | JANSSEN PHARMACEUTICA N.V. (BE) | 2006-05-02 | — | — | US | claimed |