Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | PTPRC | P08575 | 1/20 | 0.34 |
| ▸ | LIG1 | P18858 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 6/20 | 0.33 |
| ▸ | CA1 | P00915 | 6/20 | 0.33 |
| ▸ | CA9 | Q16790 | 6/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27822819 | 0.83 | CTSS (0.36) | — | |
| SCHEMBL64412 | 0.77 | ALDH1A1 (0.34) | MAPK1GAAMAPT | |
| SCHEMBL2459600 | 0.77 | — | — | |
| SCHEMBL3840978 | 0.75 | HPGD (0.38) | HPGDTSHRMAPK1HSD17B10PTPRC | |
| SCHEMBL733300 | 0.74 | ALOX5 (0.49) | TSHRMAPK1GAACYP3A4MAPT | |
| SCHEMBL4629557 | 0.74 | AGXT (0.32) | MAPK1CA12CA1CA9 | |
| SCHEMBL2502936 | 0.74 | PTPN1 (0.33) | — | |
| SCHEMBL6945091 | 0.74 | PTPN1 (0.33) | — | |
| SCHEMBL2214200 | 0.74 | ALDH1A1 (0.42) | MAPK1GAACA12CA1CA9 | |
| SCHEMBL1389283 | 0.74 | TLR8 (0.37) | TSHRMAPK1GAACA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115677600-A | 2, 3-dihydroquinazoline-4 (1H) -ketone derivative and preparation method and application thereof | 武汉大学人民医院（湖北省人民医院） | 2023-02-03 | — | — | CN | claimed |
| US-7041388-B1 | Substituted poly(arylene vinylenes), process for their preparation and their use in electroluminescent devices | SEMICONDUCTORS GMBH (DE) | 2006-05-09 | — | — | US | claimed |
| CN-115677600-B | 2, 3-Dihydro-quinazoline-4 (1H) -ketone derivative and preparation method and application thereof | 武汉大学人民医院（湖北省人民医院） | 2024-07-02 | — | — | CN | disclosed |
| CN-115677600-B | 2, 3-Dihydro-quinazoline-4 (1H) -ketone derivative and preparation method and application thereof | 武汉大学人民医院（湖北省人民医院） | 2024-07-02 | — | — | CN | disclosed |
| CN-115677600-A | 2, 3-dihydroquinazoline-4 (1H) -ketone derivative and preparation method and application thereof | 武汉大学人民医院（湖北省人民医院） | 2023-02-03 | — | — | CN | disclosed |
| CN-115677600-A | 2, 3-dihydroquinazoline-4 (1H) -ketone derivative and preparation method and application thereof | 武汉大学人民医院（湖北省人民医院） | 2023-02-03 | — | — | CN | disclosed |