SCHEMBL5888967

SCHEMBL5888967

C=CCOc1[c]cc2ccccc2c1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.37
MEN1 O00255 1/20 0.37
LMNA P02545 1/20 0.37
KMT2A Q03164 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
HPGD P15428 2/20 0.36
CA12 O43570 7/20 0.36
CA1 P00915 7/20 0.36
CA9 Q16790 7/20 0.36
TSHR P16473 1/20 0.35
MAPK1 P28482 1/20 0.35
HSD17B10 Q99714 1/20 0.35
FGFR1 P11362 1/20 0.35
PTPRC P08575 1/20 0.34
MTNR1A P48039 1/20 0.34
LIG1 P18858 1/20 0.33
CA2 P00918 1/20 0.33
CA7 P43166 1/20 0.33
ADRA2A P08913 1/20 0.33
ADRA2B P18089 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2253339 0.78 LTA4H (0.39) MAPTMEN1LMNAKMT2AMAPK1
SCHEMBL3391583 0.78 MAOA (0.46) HSD17B10
SCHEMBL3391942 0.78 MAOA (0.46) HSD17B10
SCHEMBL8681118 0.75 GPBAR1 (0.43) MEN1LMNAKMT2ACA12CA1
SCHEMBL406684 0.74 ALOX5 (0.53) MAPTMEN1LMNAKMT2ASMN1; SMN2
SCHEMBL2258966 0.74 LTA4H (0.36) MAPTMEN1LMNAKMT2ASMN1; SMN2
SCHEMBL2250260 0.74 LTA4H (0.46) MAPTSMN1; SMN2HPGDCA12CA1
SCHEMBL3822490 0.74 HPGD (0.49) MAPTLMNAHPGDCA12CA1
SCHEMBL5888989 0.73 CA12 (0.39) MAPTMEN1LMNAKMT2ASMN1; SMN2
SCHEMBL3849588 0.73 MAPT (0.44) MAPTMEN1LMNAKMT2ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7041388-B1 Substituted poly(arylene vinylenes), process for their preparation and their use in electroluminescent devices SEMICONDUCTORS GMBH (DE) 2006-05-09 US claimed