Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.71 |
| ▸ | MEN1 | O00255 | 2/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.71 |
| ▸ | POLB | P06746 | 1/20 | 0.71 |
| ▸ | PKM | P14618 | 1/20 | 0.71 |
| ▸ | NPY1R | P25929 | 1/20 | 0.71 |
| ▸ | NPY2R | P49146 | 1/20 | 0.71 |
| ▸ | PRNP | P04156 | 1/20 | 0.63 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.63 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.63 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.63 |
| ▸ | PPARG | P37231 | 1/20 | 0.63 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.63 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.63 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.63 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.63 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.63 |
| ▸ | MAPT | P10636 | 4/20 | 0.61 |
| ▸ | GAA | P10253 | 2/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2235162 | 1.00 | ALDH1A1 (0.71) | ALDH1A1MEN1KMT2APOLBPKM | |
| SCHEMBL6001705 | 0.85 | ALDH1A1 (0.57) | ALDH1A1MEN1KMT2APOLBPKM | |
| SCHEMBL6847834 | 0.83 | ALDH1A1 (1.00) | ALDH1A1MEN1KMT2APOLBPKM | |
| SCHEMBL29368058 | 0.82 | ALDH1A1 (0.61) | ALDH1A1MEN1KMT2APOLBPKM | |
| SCHEMBL9400646 | 0.80 | MAPT (0.54) | ALDH1A1MEN1KMT2APOLBPKM | |
| SCHEMBL28808509 | 0.79 | MEN1 (0.72) | ALDH1A1MEN1KMT2APOLBPKM | |
| SCHEMBL18092607 | 0.79 | MEN1 (0.72) | ALDH1A1MEN1KMT2APOLBPKM | |
| SCHEMBL3107611 | 0.79 | PRNP (0.71) | ALDH1A1MEN1KMT2APRNPCYP1A2 | |
| SCHEMBL1553071 | 0.79 | NPSR1 (0.71) | ALDH1A1MEN1KMT2APOLBPRNP | |
| SCHEMBL7155170 | 0.78 | ALDH1A1 (0.71) | ALDH1A1MEN1KMT2APOLBPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9926275-B2 | Allosteric modulators of the cannabinoid 1 receptor | NORTHEASTERN UNIVERSITY (US) | 2018-03-27 | — | — | US | disclosed |
| US-9926275-B2 | Allosteric modulators of the cannabinoid 1 receptor | NORTHEASTERN UNIVERSITY (US) | 2018-03-27 | — | — | US | disclosed |
| US-20160194284-A1 | ALLOSTERIC MODULATORS OF THE CANNABINOID 1 RECEPTOR | NORTHEASTERN UNIVERSITY (US) | 2016-07-07 | — | — | US | disclosed |
| US-20160194284-A1 | ALLOSTERIC MODULATORS OF THE CANNABINOID 1 RECEPTOR | NORTHEASTERN UNIVERSITY (US) | 2016-07-07 | — | — | US | disclosed |
| US-20160194284-A1 | ALLOSTERIC MODULATORS OF THE CANNABINOID 1 RECEPTOR | NORTHEASTERN UNIVERSITY (US) | 2016-07-07 | — | — | US | disclosed |
| WO-2015027160-A2 | ALLOSTERIC MODULATORS OF THE CANNIBINOID 1 RECEPTOR | NORTHEASTERN UNIVERSITY (US) | 2015-02-26 | — | — | WO | disclosed |
| US-7064218-B2 | Aromatic compounds and poly(oxyalkylene) containing aromatic compounds possessing antibacterial, antifungal or antitumor activity | GENELABS TECHNOLOGIES, INC. (US) | 2006-06-20 | — | — | US | disclosed |
| US-6906103-B2 | Compounds possessing antibacterial, antifungal or antitumor activity | GENELABS TECHNOLOGIES, INC. (US) | 2005-06-14 | — | — | US | disclosed |
| US-6849713-B2 | Compounds possessing antibacterial, antifungal or antitumor activity | GENELABS TECHNOLOGIES, INC. (US) | 2005-02-01 | — | — | US | disclosed |
| US-20030212113-A1 | Novel aromatic compounds and poly(oxyalkylene) containing aromatic compounds possessing antibacterial, antifungal or antitumor activity | GLAXOSMITHKLINE LLC | 2003-11-13 | — | — | US | disclosed |
| CN-1439006-A | Novel compounds possessing antibacterial, antifungal or antitumor activity | GENELABS TECH INC (US) | 2003-08-27 | — | — | CN | disclosed |
| WO-2003057212-A1 | POLYAMIDE DERIVATIVES POSSESSING ANTIBACTERIAL, ANTIFUNGAL OR ANTITUMOR ACTIVITY | GENELABS TECHNOLOGIES, INC. (US) | 2003-07-17 | — | — | WO | disclosed |
| US-20030119749-A1 | Novel compounds possessing antibacterial, antifungal or antitumor activity | SMITHKLINE BEECHAM CORPORATION | 2003-06-26 | — | — | US | disclosed |
| EP-1294713-A2 | COMPOUNDS POSSESSING ANTIBACTERIAL, ANTIFUNGAL OR ANTITUMOR ACTIVITY | GENELABS TECHNOLOGIES, INC. (US) | 2003-03-26 | — | — | EP | disclosed |
| WO-2002000650-A9 | NOVEL COMPOUNDS POSSESSING ANTIBACTERIAL, ANTIFUNGAL OR ANTITUMOR ACTIVITY | GENELABS TECH INC (US) | 2003-03-06 | — | — | WO | disclosed |
| US-20020037856-A1 | Novel compounds possessing antibacterial, antifungal or antitumor activity | GENELABS TECHNOLOGIES, INC. | 2002-03-28 | — | — | US | disclosed |
| WO-2002000650-A2 | NOVEL COMPOUNDS POSSESSING ANTIBACTERIAL, ANTIFUNGAL OR ANTITUMOR ACTIVITY | GENELABS TECHNOLOGIES, INC. (US) | 2002-01-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160194284-A1 | ALLOSTERIC MODULATORS OF THE CANNABINOID 1 RECEPTOR | CNR1, CNR2, GPR119 | ALDH1A1 2771/4885MEN1 4210/4885KMT2A 1905/4885 |
| US-20030119749-A1 | Novel compounds possessing antibacterial, antifungal or antitumor activity | CYP51A1, MCL1, ERG28 | ALDH1A1 1150/4885MEN1 68/4885KMT2A 4404/4885 |
| US-20020037856-A1 | Novel compounds possessing antibacterial, antifungal or antitumor activity | CYP51A1, MCL1, ERG28 | ALDH1A1 1150/4885MEN1 68/4885KMT2A 4404/4885 |
| US-20030212113-A1 | Novel aromatic compounds and poly(oxyalkylene) containing aromatic compounds possessing antibacterial, antifungal or antitumor activity | TYR, CYP51A1, ODC1 | ALDH1A1 597/4885MEN1 2291/4885KMT2A 3834/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.