Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | MMP8 | P22894 | 1/20 | 0.37 |
| ▸ | ACACB | O00763 | 3/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5365453 | 0.83 | ALDH1A1 (0.42) | ALDH1A1RECQLMMP8MAOB | |
| SCHEMBL5359741 | 0.81 | ALDH1A1 (0.43) | ALDH1A1RECQLLMNAKMT2ASMN1; SMN2 | |
| SCHEMBL5361416 | 0.81 | ALDH1A1 (0.43) | ALDH1A1RECQLMMP8 | |
| SCHEMBL5366585 | 0.80 | ALDH1A1 (0.42) | ALDH1A1RECQLKMT2AMEN1HSD17B10 | |
| SCHEMBL6295222 | 0.80 | ALDH1A1 (0.46) | ALDH1A1RECQLSMN1; SMN2MMP8ADAMTS4 | |
| SCHEMBL5365525 | 0.79 | ALDH1A1 (0.39) | ALDH1A1RECQL | |
| SCHEMBL5363745 | 0.79 | ACACB (0.42) | ALDH1A1RECQLLMNAKMT2ASMN1; SMN2 | |
| SCHEMBL6165524 | 0.78 | NISCH (0.45) | ALDH1A1RECQLLMNA | |
| SCHEMBL7975808 | 0.78 | ALDH1A1 (0.47) | ALDH1A1RECQLLMNASMN1; SMN2MMP8 | |
| SCHEMBL5369783 | 0.78 | ALDH1A1 (0.38) | ALDH1A1RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8114629-B2 | Site specific incorporation of keto amino acids into proteins | THE SCRIPPS RESEARCH INSTITUTE (US) | 2012-02-14 | — | — | US | disclosed |
| US-20110318806-A1 | SITE SPECIFIC INCORPORATION OF KETO AMINO ACIDS INTO PROTEINS | THE SCRIPPS RESEARCH INSTITUTE (US) | 2011-12-29 | — | — | US | disclosed |
| US-8071344-B2 | Biosynthesis; orthogonal tRNAs, orthogonal aminoacyl-tRNA synthetases | THE SCRIPPS RESEARCH INSTITUTE (US) | 2011-12-06 | — | — | US | disclosed |
| EP-2062976-B1 | Site specific incorporation of keto amino acids into proteins | SCRIPPS RESEARCH INST (US) | 2011-09-28 | — | — | EP | disclosed |
| US-20110077385-A1 | Protein arrays | THE SCRIPPS RESEARCH INSTITUTE (US) | 2011-03-31 | — | — | US | disclosed |
| US-7910345-B2 | Site specific incorporation of keto amino acids into proteins | THE SCRIPPS RESEARCH INSTITUTE (US) | 2011-03-22 | — | — | US | disclosed |
| US-7834159-B2 | Pharmacokinetics; glycosyltransferases; vaccines | THE SCRIPPS RESEARCH INSTITUTE (US) | 2010-11-16 | — | — | US | disclosed |
| US-7825226-B2 | Pharmacokinetics; glycosyltransferases | THE SCRIPPS RESEARCH INSTITUTE (US) | 2010-11-02 | — | — | US | disclosed |
| US-20100009425-A1 | Glycoprotein synthesis | THE SCRIPPS RESEARCH INSTITUTE (US) | 2010-01-14 | — | — | US | disclosed |
| US-7642085-B2 | Polypeptide incorporating unnatural amino acid chemically bonded to solid support by a chemical linkage | THE SCRIPPS RESEARCH INSTITUTE (US) | 2010-01-05 | — | — | US | disclosed |
| US-20050209133-A1 | Glycoprotein synthesis | THE SCRIPPS RESEARCH INSTITUTE (US) | 2005-09-22 | — | — | US | disclosed |
| US-20050186656-A1 | Glycoprotein synthesis | THE SCRIPPS RESEARCH INSTITUTE (US) | 2005-08-25 | — | — | US | disclosed |
| US-20050181471-A1 | Glycoprotein synthesis | THE SCRIPPS RESEARCH INSTITUTE (US) | 2005-08-18 | — | — | US | disclosed |
| US-6927042-B2 | Glycoprotein synthesis | THE SCRIPPS RESEARCH INSTITUTE (US) | 2005-08-09 | — | — | US | disclosed |
| EP-1558747-A2 | GLYCOPROTEIN SYNTHESIS | The Scripps Research Institute (US) | 2005-08-03 | — | — | EP | disclosed |
| US-20040198637-A1 | Polypeptide incorporating unnatural amino acid chemically bonded to solid support by a chemical linkage | THE SCRIPPS RESEARCH INSTITUTE | 2004-10-07 | — | — | US | disclosed |
| WO-2004058946-A2 | PROTEIN ARRAYS | THE SCRIPPS RESEARCH INSTITUTE (US) | 2004-07-15 | — | — | WO | disclosed |
| US-20040138106-A1 | Glycoprotein synthesis | THE SCRIPPS RESEARCH INSTITUTE | 2004-07-15 | — | — | US | disclosed |
| WO-2004035743-A2 | SITE SPECIFIC INCORPORATION OF KETO AMINO ACIDS INTO PROTEINS | THE SCRIPPS RESEARCH INSTITUTE (US) | 2004-04-29 | — | — | WO | disclosed |
| WO-2004035605-A2 | GLYCOPROTEIN SYNTHESIS | THE SCRIPPS RESEARCH INSTITUTE (US) | 2004-04-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050181471-A1 | Glycoprotein synthesis | UGGT1, ST6GAL1, ANPEP | ALDH1A1 1524/4885RECQL 4882/4885LMNA 3304/4885 |
| US-20050186656-A1 | Glycoprotein synthesis | UGGT1, ST6GAL1, ANPEP | ALDH1A1 1524/4885RECQL 4882/4885LMNA 3304/4885 |
| US-20110077385-A1 | Protein arrays | MAX, MRPL21, STUB1 | ALDH1A1 3707/4885RECQL 3962/4885LMNA 4345/4885 |
| US-20040138106-A1 | Glycoprotein synthesis | UGGT1, ST6GAL1, ANPEP | ALDH1A1 1524/4885RECQL 4882/4885LMNA 3304/4885 |
| US-20040198637-A1 | Polypeptide incorporating unnatural amino acid chemically bonded to solid support by a chemical linkage | DNPEP, NPEPPS, ANPEP | ALDH1A1 2931/4885RECQL 4423/4885LMNA 4155/4885 |
| US-20050209133-A1 | Glycoprotein synthesis | UGGT1, ST6GAL1, ANPEP | ALDH1A1 1524/4885RECQL 4882/4885LMNA 3304/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.