Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.34 |
| ▸ | RXRA | P19793 | 4/20 | 0.34 |
| ▸ | RXRB | P28702 | 4/20 | 0.34 |
| ▸ | RXRG | P48443 | 4/20 | 0.34 |
| ▸ | FAAH | O00519 | 2/20 | 0.33 |
| ▸ | MGLL | Q99685 | 2/20 | 0.33 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.32 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.32 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.32 |
| ▸ | PTGES | O14684 | 1/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
| ▸ | RGS4 | P49798 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2456324 | 0.89 | FAAH (0.41) | NPSR1GAAHTTGPR55RXRA | |
| SCHEMBL15094146 | 0.89 | NR1H2 (0.40) | NPSR1GAAHTTGPR55RXRA | |
| SCHEMBL6095174 | 0.79 | GAA (0.44) | NPSR1GAAHTTGPR55FAAH | |
| SCHEMBL14031439 | 0.79 | MAPT (0.49) | NPSR1MGLLNR1H2NR1H3RGS4 | |
| SCHEMBL18327868 | 0.78 | NR1H2 (0.44) | GAAHTTFAAHMGLLNR1H2 | |
| SCHEMBL15093852 | 0.76 | CES2 (0.43) | NPSR1NR1H2NR1H3 | |
| SCHEMBL14031339 | 0.76 | NR1H2 (0.54) | GAANR1H2NR1H3MEN1ALDH1A1 | |
| SCHEMBL10050134 | 0.75 | NR1H2 (0.46) | HTTFAAHMGLLNR1H2NR1H3 | |
| SCHEMBL14049757 | 0.74 | MAPT (0.45) | NPSR1NR1H2NR1H3RGS4MEN1 | |
| SCHEMBL2457394 | 0.74 | CMA1 (0.46) | GAANR1H2NR1H3MEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7060843-B1 | Electroluminescent devices comprising diketopyrrolopyrroles | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2006-06-13 | — | — | US | disclosed |
| US-7001677-B2 | Electroluminescent devices comprising diketopyrrolopyrroles | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2006-02-21 | — | — | US | disclosed |
| US-20040009368-A1 | Electroluminescent devices comprising diketopyrrolopyrroles | OTANI JUNJI (JP) | 2004-01-15 | — | — | US | disclosed |
| EP-1087006-B1 | Electroluminescent devices comprising diketopyrrolopyrroles | CIBA SC HOLDING AG (CH) | 2003-10-15 | — | — | EP | disclosed |
| EP-1329493-A2 | Electroluminescent devices comprising diketopyrrolopyrroles | Ciba SC Holding AG (CH) | 2003-07-23 | — | — | EP | disclosed |
| EP-1087006-A1 | Electroluminescent devices comprising diketopyrrolopyrroles | Ciba SC Holding AG (CH) | 2001-03-28 | — | — | EP | disclosed |