SCHEMBL2456324

SCHEMBL2456324

CC(C)(C)c1cc(CN2C(=O)C3=C(c4ccc(-c5ccccc5)cc4)N(Cc4cc(C(C)(C)C)cc(C(C)(C)C)c4)C(=O)C3=C2c2ccc(-c3ccccc3)cc2)cc(C(C)(C)C)c1

nearest known ligand 0.41

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
FAAH O00519 1/20 0.41
MGLL Q99685 1/20 0.41
RXRA P19793 5/20 0.40
RXRB P28702 5/20 0.40
RXRG P48443 3/20 0.40
NR1H2 P55055 3/20 0.38
NR1H3 Q13133 3/20 0.38
GAA P10253 1/20 0.37
HTT P42858 1/20 0.37
NPSR1 Q6W5P4 1/20 0.37
GPR55 Q9Y2T6 1/20 0.37
PPARG P37231 1/20 0.36
PPARD Q03181 1/20 0.36
PPARA Q07869 1/20 0.36
CHRM5 P08912 2/20 0.36
RGS4 P49798 1/20 0.35
EGFR P00533 1/20 0.34
EP300 Q09472 1/20 0.33
SERPINE1 P05121 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15094146 0.97 NR1H2 (0.40) FAAHMGLLRXRARXRBRXRG
SCHEMBL5892102 0.89 NPSR1 (0.34) FAAHMGLLRXRARXRBRXRG
SCHEMBL6095174 0.85 GAA (0.44) FAAHMGLLNR1H2NR1H3GAA
SCHEMBL15093852 0.83 CES2 (0.43) NR1H2NR1H3NPSR1CHRM5
SCHEMBL2457394 0.81 CMA1 (0.46) NR1H2NR1H3GAACHRM5SERPINE1
SCHEMBL16232291 0.78 HSP90AA1 (0.39) NR1H2NR1H3HTTCHRM5
SCHEMBL5073360 0.77 NR1H2 (0.57) FAAHMGLLNR1H2NR1H3NPSR1
SCHEMBL5892099 0.72 NR1H2 (0.57) FAAHMGLLNR1H2NR1H3RGS4
SCHEMBL598840 0.71 KMT2A (0.42) GAAHTTNPSR1RGS4
SCHEMBL9835835 0.69 NR1H2 (0.56) MGLLNR1H2NR1H3NPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2365735-B1 Luminescent element material and luminescent element comprising the same TORAY INDUSTRIES (JP) 2013-08-28 EP disclosed
EP-2365735-A2 Luminescent element material and luminescent element comprising the same TORAY INDUSTRIES INC. (JP) 2011-09-14 EP disclosed
US-7318966-B2 Luminescent element material and luminescent element comprising the same TORAY INDUSTRIES, INC. (JP) 2008-01-15 US disclosed
US-20030168970-A1 Luminescent element material and luminescent element comprising the same TORAY INDUSTRIES, INC. (JP) 2003-09-11 US disclosed
EP-1341403-A1 LUMINESCENT ELEMENT MATERIAL AND LUMINESCENT ELEMENT COMPRISING THE SAME Toray Industries, Inc. (JP) 2003-09-03 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030168970-A1 Luminescent element material and luminescent element comprising the same SAAL1, EBPL, CSNK1A1L FAAH 4261/4885MGLL 944/4885RXRA 1389/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.