Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 2/20 | 0.60 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.60 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | YAP1 | P46937 | 1/20 | 0.48 |
| ▸ | BCL2 | P10415 | 1/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.47 |
| ▸ | CTSS | P25774 | 6/20 | 0.47 |
| ▸ | CTSK | P43235 | 5/20 | 0.47 |
| ▸ | HRH2 | P25021 | 1/20 | 0.46 |
| ▸ | HRH1 | P35367 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | CTSL | P07711 | 1/20 | 0.46 |
| ▸ | CTSB | P07858 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2728593 | 1.00 | ITGB3 (0.60) | ITGB3ITGA2BKLK5HDAC8MEN1 | |
| SCHEMBL16173545 | 0.91 | ITGB3 (0.56) | ITGB3ITGA2BKLK5HDAC8MEN1 | |
| SCHEMBL14365476 | 0.91 | ITGB3 (0.56) | ITGB3ITGA2BKLK5HDAC8MEN1 | |
| SCHEMBL13367276 | 0.89 | ITGB3 (0.61) | ITGB3ITGA2BKLK5HDAC8MEN1 | |
| SCHEMBL16815979 | 0.89 | ITGB3 (0.64) | ITGB3ITGA2BKLK5HDAC8MEN1 | |
| SCHEMBL4937967 | 0.89 | ITGB3 (0.61) | ITGB3ITGA2BKLK5HDAC8MEN1 | |
| SCHEMBL5727469 | 0.89 | ITGB3 (0.74) | ITGB3ITGA2BHDAC8BCL2PTPN1 | |
| SCHEMBL15593763 | 0.89 | ITGB3 (0.64) | ITGB3ITGA2BKLK5HDAC8MEN1 | |
| SCHEMBL4937975 | 0.89 | ITGB3 (0.61) | ITGB3ITGA2BKLK5HDAC8MEN1 | |
| SCHEMBL2728905 | 0.89 | ITGB3 (0.74) | ITGB3ITGA2BHDAC8BCL2PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7071221-B2 | Heterocyclic oxime compounds | LES LABORATOIRES SERVIER (FR) | 2006-07-04 | — | — | US | disclosed |
| US-20050026973-A1 | New heterocyclic oxime compounds | LES LABORATOIRES SERVIER (FR) | 2005-02-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050026973-A1 | New heterocyclic oxime compounds | CBR3, CBR1, CYB5R3 | ITGB3 1994/4885ITGA2B 2238/4885KLK5 4745/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.