Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGKA | P23743 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.53 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.53 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.53 |
| ▸ | NAAA | Q02083 | 1/20 | 0.52 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.51 |
| ▸ | HTR2C | P28335 | 1/20 | 0.50 |
| ▸ | PAM | P19021 | 2/20 | 0.47 |
| ▸ | PRKCA | P17252 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | RAD52 | P43351 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4334518 | 0.92 | DGKA (0.74) | DGKAALDH1A1PRSS1PRSS2PRSS3 | |
| SCHEMBL1681496 | 0.92 | ALDH1A1 (0.69) | DGKAALDH1A1PRSS1PRSS2PRSS3 | |
| SCHEMBL3502294 | 0.92 | DGKA (0.74) | DGKAALDH1A1PRSS1PRSS2PRSS3 | |
| SCHEMBL18675745 | 0.92 | DGKA (0.74) | DGKAALDH1A1PRSS1PRSS2PRSS3 | |
| SCHEMBL13347191 | 0.92 | DGKA (0.74) | DGKAALDH1A1PRSS1PRSS2PRSS3 | |
| SCHEMBL26238726 | 0.92 | DGKA (0.74) | DGKAALDH1A1PRSS1PRSS2PRSS3 | |
| SCHEMBL16201842 | 0.90 | ALDH1A1 (0.56) | DGKAALDH1A1PRSS1PRSS2PRSS3 | |
| SCHEMBL13572526 | 0.89 | DGKA (0.57) | DGKAALDH1A1PRSS1PRSS2PRSS3 | |
| SCHEMBL31126278 | 0.88 | DGKA (0.80) | DGKAALDH1A1PRSS1PRSS2PRSS3 | |
| SCHEMBL31493856 | 0.88 | DGKA (0.80) | DGKAALDH1A1PRSS1PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120116093-A1 | ONE POT PROCESS FOR PREPARING 2-BUTYL-3-[[2'-(1H-TETRAZOL-5-YL)[1,1'-BIPHENYL]-4-YL]METHYL]-1,3-DIAZASPIRO [4, 4] NON-1-EN-4-ONE (IRBESARTAN) | CTX Life Sciences Pvt. Ltd (IN) | 2012-05-10 | — | — | US | claimed |
| EP-2417110-A2 | A ONE POT PROCESS FOR PREPARING 2-BUTYL-3-[[2'-(1H-TETRAZOL-5-YL)[1,1'-BIPHENYL]-4-YL]METHYL]-1,3-DIAZASPIRO [4, 4]NON-1-EN-4-ONE (IRBESARTAN) | CTX Life Sciences Pvt. Ltd. (IN) | 2012-02-15 | — | — | EP | claimed |
| WO-2010116380-A2 | A ONE POT PROCESS FOR PREPARING 2-BUTYL-3-[[2'-(1H-TETRAZOL-5-YL)[1,1'-BIPHENYL]-4-YL]METHYL]-1,3-DIAZASPIRO [4, 4] NON-1-EN-4-ONE (IRBESARTAN) | CTX LIFE SCIENCES PVT. LTD. (IN) | 2010-10-14 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120116093-A1 | ONE POT PROCESS FOR PREPARING 2-BUTYL-3-[[2'-(1H-TETRAZOL-5-YL)[1,1'-BIPHENYL]-4-YL]METHYL]-1,3-DIAZASPIRO [4, 4] NON-1-EN-4-ONE (IRBESARTAN) | PKD1, AGTR1, NPR1 | DGKA 3706/4885ALDH1A1 1302/4885PRSS1 3047/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.