Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.47 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 4/20 | 0.44 |
| ▸ | GRK2 | P25098 | 1/20 | 0.44 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.44 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.44 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5896951 | 0.86 | NPSR1 (0.53) | LMNAMAPTNPSR1RXFP1TAS1R3 | |
| SCHEMBL5896878 | 0.82 | MAPT (0.47) | LMNAMAPTNPSR1RXFP1TAS1R3 | |
| SCHEMBL5896454 | 0.78 | ITGB1 (0.53) | LMNAMAPTNPSR1TAS1R3TAS1R1 | |
| SCHEMBL5897280 | 0.74 | ITGB1 (0.53) | LMNAMAPTNPSR1KMT2AMEN1 | |
| SCHEMBL7299127 | 0.74 | TAS1R3 (0.57) | LMNAMAPTNPSR1RXFP1TAS1R3 | |
| SCHEMBL7876448 | 0.74 | POLB (0.58) | LMNAMAPTNPSR1TAS1R3TAS1R1 | |
| SCHEMBL7876199 | 0.72 | HPGD (0.52) | LMNAMAPTNPSR1TAS1R3TAS1R1 | |
| SCHEMBL5897651 | 0.72 | ROCK2 (0.62) | LMNAMAPTTAS1R3TAS1R1ALDH1A1 | |
| SCHEMBL7872607 | 0.71 | TAS1R3 (0.53) | LMNAMAPTNPSR1TAS1R3TAS1R1 | |
| SCHEMBL5897049 | 0.71 | POLB (0.54) | LMNAMAPTNPSR1TAS1R3TAS1R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7091242-B2 | Beta-amino acid derivatives as integrin receptor antagonists | BAYER AKTIENGESELLSCHAFT (DE) | 2006-08-15 | — | — | US | disclosed |
| US-20040058904-A1 | Beta-amino acid derivatives as integrin receptor antagonists | BAYER AKTIENGESELLSCHAFT (DE) | 2004-03-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040058904-A1 | Beta-amino acid derivatives as integrin receptor antagonists | ITGAL, ITGB1, ITGB2 | LMNA 2349/4885MAPT 2980/4885NPSR1 344/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.