Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.41 |
| ▸ | ZAP70 | P43403 | 1/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | RAD52 | P43351 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.39 |
| ▸ | CRHBP | P24387 | 1/20 | 0.39 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.38 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5897129 | 0.82 | HRH4 (0.55) | HRH3KDM4EALDH1A1KMT2ACRHBP | |
| SCHEMBL5897044 | 0.77 | HRH4 (0.50) | KDM4EALDH1A1KMT2AGFERCRHBP | |
| SCHEMBL4781313 | 0.77 | KMT2A (0.51) | KDM4EALDH1A1GAAMAPTRAB9A | |
| SCHEMBL7676555 | 0.73 | CYP1A2 (0.50) | MAPTRAB9AKMT2ASMN1; SMN2CRHBP | |
| SCHEMBL28606435 | 0.70 | MAPT (0.56) | PIK3CAKDM4EALDH1A1GAAMAPT | |
| SCHEMBL9906196 | 0.69 | KDM4E (0.48) | HRH3CHRNA7KDM4EALDH1A1GAA | |
| Water SCHEMBL7481158 | 0.69 | — | — | |
| SCHEMBL10272705 | 0.68 | KMT2A (0.53) | PIK3CAKDM4EALDH1A1GAAMAPT | |
| SCHEMBL5897067 | 0.68 | ALDH1A1 (0.43) | HRH3PIK3CAALDH1A1KMT2ACRHBP | |
| SCHEMBL5897076 | 0.68 | KDM4E (0.46) | HRH3KDM4EALDH1A1GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7060700-B2 | Amide derivatives useful as inhibitors of the production of cytokines | ASTRAZENECA AB (SE) | 2006-06-13 | — | — | US | disclosed |