SCHEMBL5898437

SCHEMBL5898437

COc1ccc(P(=O)(C(=O)c2c(OC)ccc3ccccc23)C(=O)c2c(OC)ccc3ccccc23)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.46
MMP3 P08254 3/20 0.46
ABCG2 Q9UNQ0 1/20 0.45
KMT2A Q03164 6/20 0.44
NPC1 O15118 5/20 0.44
RAB9A P51151 3/20 0.44
MEN1 O00255 5/20 0.43
KDM4E B2RXH2 2/20 0.43
ALDH1A1 P00352 2/20 0.43
HPGD P15428 2/20 0.43
POLB P06746 2/20 0.43
LMNA P02545 1/20 0.43
PKM P14618 1/20 0.43
HTT P42858 1/20 0.43
BLM P54132 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
CNR2 P34972 2/20 0.42
CTSD P07339 1/20 0.42
CNR1 P21554 1/20 0.42
MTNR1A P48039 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29372113 0.90 MAPT (0.46) MAPTABCG2KMT2ANPC1RAB9A
SCHEMBL10623233 0.90 MAPT (0.46) MAPTABCG2KMT2ANPC1RAB9A
SCHEMBL56880 0.89 SMN1; SMN2 (0.47) MAPTMMP3KMT2ANPC1RAB9A
SCHEMBL5898511 0.88 MMP3 (0.43) MAPTMMP3ABCG2KMT2AMEN1
SCHEMBL2772458 0.87 ABCG2 (0.48) MAPTMMP3ABCG2KMT2ANPC1
SCHEMBL68727 0.80 MAPT (0.46) MAPTABCG2KMT2ANPC1RAB9A
SCHEMBL31484246 0.80 MAPT (0.46) MAPTABCG2KMT2ANPC1RAB9A
SCHEMBL11574652 0.79 ALDH1A1 (0.54) MAPTMMP3ABCG2KMT2ANPC1
SCHEMBL7637230 0.77 NPC1 (0.46) MAPTKMT2ANPC1RAB9AMEN1
SCHEMBL5898571 0.75 CNR2 (0.42) MAPTABCG2KMT2ANPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7049350-B2 Polymerizable compound, polymerizable composition and cured product containing the compound SHOWA DENKO K.K. (JP) 2006-05-23 US disclosed
US-20040235980-A1 Polymerizable compound, polymerizable composition and cured product containing the compound SHOWA DENKO K.K. (JP) 2004-11-25 US disclosed
WO-2003010124-A1 POLYMERIZABLE COMPOUND, polymeRIZABLE COMPOSITION AND CURED PRODUCT CONTAINING THE COMPOUND SHOWA DENKO K. K. (JP) 2003-02-06 WO disclosed