SCHEMBL5898571

SCHEMBL5898571

COc1ccc2ccccc2c1C(=O)P(=O)(C(=O)c1c(OC)ccc2ccccc12)c1cc(C)ccc1C

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 2/20 0.42
CNR1 P21554 1/20 0.42
KMT2A Q03164 4/20 0.40
MEN1 O00255 3/20 0.40
POLB P06746 2/20 0.40
MAPT P10636 2/20 0.40
KDM4E B2RXH2 2/20 0.40
HPGD P15428 2/20 0.40
AHR P35869 1/20 0.40
CTSD P07339 1/20 0.40
ABCG2 Q9UNQ0 1/20 0.40
ALDH1A1 P00352 1/20 0.40
LMNA P02545 1/20 0.40
PKM P14618 1/20 0.40
HTT P42858 1/20 0.40
BLM P54132 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
NPC1 O15118 2/20 0.39
RAB9A P51151 2/20 0.39
MTNR1A P48039 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL57625 0.87 TAS1R3 (0.42) CNR2KMT2AMEN1POLBSMN1; SMN2
SCHEMBL29374425 0.87 TAS1R3 (0.42) CNR2KMT2AMEN1POLBSMN1; SMN2
SCHEMBL711411 0.83 NPC1 (0.46) KMT2AMEN1POLBMAPTHPGD
SCHEMBL29372199 0.83 MEN1 (0.38) CNR2KMT2AMEN1POLBABCG2
SCHEMBL58468 0.83 MEN1 (0.38) CNR2KMT2AMEN1POLBABCG2
SCHEMBL23295616 0.80 NPC1 (0.43) KMT2AMEN1POLBHPGDAHR
SCHEMBL10623233 0.78 MAPT (0.46) CNR2CNR1KMT2AMEN1POLB
SCHEMBL29372113 0.78 MAPT (0.46) CNR2CNR1KMT2AMEN1POLB
SCHEMBL5898437 0.75 MAPT (0.46) CNR2CNR1KMT2AMEN1POLB
SCHEMBL5898511 0.74 MMP3 (0.43) CNR2CNR1KMT2AMEN1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7049350-B2 Polymerizable compound, polymerizable composition and cured product containing the compound SHOWA DENKO K.K. (JP) 2006-05-23 US disclosed
US-20040235980-A1 Polymerizable compound, polymerizable composition and cured product containing the compound SHOWA DENKO K.K. (JP) 2004-11-25 US disclosed
US-4868091-A USING A BISACYLPHOSPHINE OXIDE PHOTOINITIATOR, UNSATURATED COMPOUND AND POLYMERIC BINDER; SHORT EXPOSURE TIME; NEWSPAPER PRINTING BASF AKTIENGESELLSCHAFT (DE) 1989-09-19 US disclosed