SCHEMBL5898511

SCHEMBL5898511

COc1ccc2ccccc2c1C(=O)P(=O)(C(=O)c1c(OC)ccc2ccccc12)c1ccc(-c2ccccc2)cc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MMP3 P08254 3/20 0.43
MAPT P10636 2/20 0.42
KDM4E B2RXH2 2/20 0.42
ALDH1A1 P00352 2/20 0.42
SMN1; SMN2 Q16637 2/20 0.42
CTSD P07339 1/20 0.42
MEN1 O00255 1/20 0.42
LMNA P02545 1/20 0.42
POLB P06746 1/20 0.42
PKM P14618 1/20 0.42
HPGD P15428 1/20 0.42
HTT P42858 1/20 0.42
BLM P54132 1/20 0.42
KMT2A Q03164 1/20 0.42
CNR2 P34972 2/20 0.42
CNR1 P21554 1/20 0.42
MTNR1A P48039 1/20 0.41
MTNR1B P49286 1/20 0.41
CYP1A2 P05177 1/20 0.41
CYP3A4 P08684 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5898437 0.88 MAPT (0.46) MMP3MAPTKDM4EALDH1A1SMN1; SMN2
SCHEMBL29372113 0.86 MAPT (0.46) MAPTKDM4EALDH1A1SMN1; SMN2CTSD
SCHEMBL10623233 0.86 MAPT (0.46) MAPTKDM4EALDH1A1SMN1; SMN2CTSD
SCHEMBL56880 0.83 SMN1; SMN2 (0.47) MMP3MAPTKDM4EALDH1A1SMN1; SMN2
SCHEMBL2770469 0.83 TAS1R3 (0.42) MMP3KDM4EALDH1A1SMN1; SMN2MEN1
SCHEMBL68727 0.81 MAPT (0.46) MAPTKDM4EALDH1A1SMN1; SMN2CTSD
SCHEMBL31484246 0.81 MAPT (0.46) MAPTKDM4EALDH1A1SMN1; SMN2CTSD
SCHEMBL979842 0.76 CA12 (0.58) MAPTKDM4EALDH1A1SMN1; SMN2CTSD
SCHEMBL2772458 0.75 ABCG2 (0.48) MMP3MAPTKDM4EALDH1A1MEN1
SCHEMBL23535325 0.74 CNR2 (0.43) MMP3MAPTKDM4EALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 117 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12024136-B2 Ultra-fast curing scratch-resistant headlight restoration coating ILLINOIS TOOL WORKS INC. (US) 2024-07-02 US claimed
EP-4514304-B1 DENTAL COMPOSITION CONTAINING A RESORCINOL OR CATECHOL MOIETY CONTAINING COMPONENT AND USE THEREOF SOLVENTUM INTELLECTUAL PROPERTIES COMPANY (US) 2026-03-25 EP disclosed
US-12577340-B2 Storage stable two-component dual cure dental composition SOLVENTUM INTELLECTUAL PROPERTIES COMPANY (US) 2026-03-17 US disclosed
US-20260028440-A1 Curable Composition for Producing Transparent Orthodontic Attachments SOLVENTUM INTELLECTUAL PROPERTIES COMPANY (US) 2026-01-29 US disclosed
EP-4629958-A1 SURFACE-TREATED FILLER, DENTAL COMPOSITION CONTAINING SUCH A FILLER, PROCESS OF PRODUCTION AND USE THEREOF Solventum Intellectual Properties Company (US) 2025-10-15 EP disclosed
EP-4329704-B1 INITIATOR SYSTEM WITH POLYMERIZABLE THIOUREA COMPONENT, DENTAL COMPOSITION AND USE THEREOF SOLVENTUM INTELLECTUAL PROPERTIES COMPANY (US) 2025-10-08 EP disclosed
EP-3880156-B1 STORAGE STABLE TWO-COMPONENT DUAL CURE DENTAL COMPOSITION SOLVENTUM INTELLECTUAL PROPERTIES COMPANY (US) 2025-08-20 EP disclosed
US-20250235390-A1 Composition and Process for Treating a Disorder in the Oral Cavity of a Mammal SOLVENTUM INTELLECTUAL PROPERTIES COMPANY 2025-07-24 US disclosed
EP-4580818-A1 ONE COMPONENT, UV-CURED PRIMER MATERIAL FOR REPAIRING SURFACE IMPERFECTIONS Illinois Tool Works Inc. (US) 2025-07-09 EP disclosed
EP-4558086-A1 CURABLE COMPOSITION FOR PRODUCING TRANSPARENT ORTHODONTIC ATTACHMENTS Solventum Intellectual Properties Company (US) 2025-05-28 EP disclosed
WO-2015126865-A1 ADHESIVE BONDING COMPOSITION AND USE THEREOF 3M INNOVATIVE PROPERTIES COMPANY (US) 2015-08-27 WO disclosed
WO-2015034977-A1 DENTAL COMPOSITION CONTAINING POLYOXOMETALATES, PROCESS OF PRODUCTION AND USE THEREOF 3M INNOVATIVE PROPERTIES COMPANY (US) 2015-03-12 WO disclosed
US-20140329205-A1 ONE COMPONENT SELF-ADHESIVE DENTAL COMPOSITION, PROCESS OF PRODUCTION AND USE THEREOF SOLVENTUM INTELLECTUAL PROPERTIES COMPANY 2014-11-06 US disclosed
EP-2785307-A1 ONE COMPONENT SELF-ADHESIVE DENTAL COMPOSITION, PROCESS OF PRODUCTION AND USE THEREOF 3M Innovative Properties Company (US) 2014-10-08 EP disclosed
WO-2013082337-A1 ONE COMPONENT SELF-ADHESIVE DENTAL COMPOSITION, PROCESS OF PRODUCTION AND USE THEREOF 3M INNOVATIVE PROPERTIES COMPANY (US) 2013-06-06 WO disclosed
US-7049350-B2 Polymerizable compound, polymerizable composition and cured product containing the compound SHOWA DENKO K.K. (JP) 2006-05-23 US disclosed
US-20040235980-A1 Polymerizable compound, polymerizable composition and cured product containing the compound SHOWA DENKO K.K. (JP) 2004-11-25 US disclosed
WO-2003010124-A1 POLYMERIZABLE COMPOUND, polymeRIZABLE COMPOSITION AND CURED PRODUCT CONTAINING THE COMPOUND SHOWA DENKO K. K. (JP) 2003-02-06 WO disclosed
US-4792632-A ADDITION POLYMER PHOTOINITIATORS ESPE FABRIK PHARMAZEUTISCHER PRAPARATE GMBH (DE) 1988-12-20 US disclosed
US-4737593-A PHOTOINITIATORS FOR ADDITION POLYMERIZATION; DENTISTRY Fabrik Pharmazeutischer Praparate (DE) 1988-04-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140329205-A1 ONE COMPONENT SELF-ADHESIVE DENTAL COMPOSITION, PROCESS OF PRODUCTION AND USE THEREOF ESD, CAD, GSS MMP3 4261/4885MAPT 486/4885KDM4E 2607/4885
US-20260028440-A1 Curable Composition for Producing Transparent Orthodontic Attachments SMCHD1, SMC2, SMC1A MMP3 2203/4885MAPT 185/4885KDM4E 458/4885
US-20250235390-A1 Composition and Process for Treating a Disorder in the Oral Cavity of a Mammal GSDMD, PIGS, GANC MMP3 469/4885MAPT 2591/4885KDM4E 3077/4885
US-12577340-B2 Storage stable two-component dual cure dental composition GPX4, SSRP1, H1-0 MMP3 4211/4885MAPT 1702/4885KDM4E 1053/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.