Sugi Predict

Sugi Predict / Compounds / SCHEMBL5898461

SCHEMBL5898461

SCHEMBL5898461

N[C@H](CC(=O)OCc1ccccc1)C(=O)O

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ SLC15A1 P46059 2/20 0.65
▸ ALDH1A1 P00352 3/20 0.58
▸ MAPK1 P28482 1/20 0.58
▸ L3MBTL1 Q9Y468 1/20 0.58
▸ SLC1A1 P43005 6/20 0.56
▸ SLC1A3 P43003 5/20 0.55
▸ ALPI P09923 1/20 0.55
▸ PKM P14618 1/20 0.55
▸ PTGS1 P23219 1/20 0.55
▸ XIAP P98170 1/20 0.55
▸ SLC7A5 Q01650 1/20 0.55
▸ LTA4H P09960 1/20 0.52
▸ SLC1A2 P43004 4/20 0.51
▸ KMT2A Q03164 2/20 0.50
▸ MEN1 O00255 1/20 0.50
▸ CYP1A2 P05177 1/20 0.50
▸ CYP2D6 P10635 1/20 0.50
▸ CYP2C9 P11712 1/20 0.50
▸ CYP2C19 P33261 1/20 0.50
▸ GRIK1 P39086 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL730848 1.00 SLC15A1 (0.65) SLC15A1ALDH1A1MAPK1L3MBTL1SLC1A1
SCHEMBL4523936 1.00 SLC15A1 (0.65) SLC15A1ALDH1A1MAPK1L3MBTL1SLC1A1
Hydrochloric Acid SCHEMBL14482670 0.98 SLC15A1 (0.63) SLC15A1ALDH1A1MAPK1L3MBTL1SLC1A1
Hydrochloric Acid SCHEMBL14482674 0.98 SLC15A1 (0.63) SLC15A1ALDH1A1MAPK1L3MBTL1SLC1A1
Phenylalanine SCHEMBL744817 0.94 SLC15A1 (0.71) SLC15A1ALDH1A1MAPK1L3MBTL1SLC1A1
Aspartic Acid SCHEMBL28852564 0.91 SLC15A1 (0.56) SLC15A1ALDH1A1MAPK1L3MBTL1SLC1A1
SCHEMBL589203 0.90 SLC15A1 (0.61) SLC15A1ALDH1A1MAPK1L3MBTL1SLC1A1
SCHEMBL1264374 0.90 SLC15A1 (0.61) SLC15A1ALDH1A1MAPK1L3MBTL1SLC1A1
SCHEMBL589202 0.90 SLC15A1 (0.61) SLC15A1ALDH1A1MAPK1L3MBTL1SLC1A1
SCHEMBL32681189 0.90 SLC15A1 (0.61) SLC15A1ALDH1A1MAPK1L3MBTL1SLC1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 98 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113882157-B Polyether-polyamino acid sizing agent and preparation method and application thereof 中国石油化工股份有限公司 2023-08-04 — — CN claimed
JP-57028099-A — — None — — JP disclosed
EP-4656201-A2 RAS INHIBITORS Revolution Medicines, Inc. (US) 2025-12-03 — — EP disclosed
US-20250195521-A1 USE OF SOS1 INHIBITORS TO TREAT MALIGNANCIES WITH SHP2 MUTATIONS Revolution Medicines, Inc. 2025-06-19 — — US disclosed
CN-120044169-A Method for detecting carbobenzoxy-L-alanine by high performance liquid chromatography 武汉武药制药有限公司 2025-05-27 — — CN disclosed
US-12252497-B2 Ras inhibitors Revolution Medicines, Inc. (US) 2025-03-18 — — US disclosed
US-20250051306-A1 RAS INHIBITORS WILMINGTON TRUST, NATIONAL ASSOCIATION, AS AGENT 2025-02-13 — — US disclosed
EP-4425181-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTE Bertis Inc (KR) 2024-09-04 — — EP disclosed
US-20240277796-A1 METHODS FOR INHIBITING RAS WILMINGTON TRUST, NATIONAL ASSOCIATION, AS AGENT 2024-08-22 — — US disclosed
US-20240262847-A1 COVALENT RAS INHIBITORS AND USES THEREOF WILMINGTON TRUST, NATIONAL ASSOCIATION, AS AGENT 2024-08-08 — — US disclosed
US-4459235-A 2-Cyanosteroids G. D. SEARLE & CO. (US) 1984-07-10 — — US disclosed
US-4436918-A FROM A 2,5-DIOXOPYRROLIDINE COMPOUND TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1984-03-13 — — US disclosed
JP-S5728099-A 2-AMINO-L-THREOPENTOSE DERIVATIVE KUMIAI CHEM IND CO LTD 1982-02-15 — — JP disclosed
US-4299767-A ANTIALDOSTERONES, HYPOTENSIVE AGENTS, TREATMENT OF HEART AND LEVER DISORDERS HOFFMANN-LA ROCHE INC. (US) 1981-11-10 — — US disclosed
US-4296031-A ALDOSTERONE ANTAGONIST HOFFMANN-LA ROCHE INC. (US) 1981-10-20 — — US disclosed
US-4294758-A ANTICHOLESTEROL AGENTS, CARDIOVASCULAR DISORDERS HOFFMANN-LA ROCHE INC. (US) 1981-10-13 — — US disclosed
US-4281188-A ANTIALDOSTERONES HOFFMANN-LA ROCHE INC. (US) 1981-07-28 — — US disclosed
US-4251443-A ALDOSTERONE ANTAGONISTS; PREVENTION OF HEART FAILURE, HEPATIC ASCITES, ALDOSTERONISM, HYPERTENSION HOFFMANN-LA ROCHE INC. (US) 1981-02-17 — — US disclosed
US-4087520-A Lowering blood pressure with new L-3-(3,4-dihydroxyphenyl)-2-methyl-alanine peptides BOEHRINGER MANNHEIM GMBH (DT) 1978-05-02 — — US disclosed
US-4012367-A Anti-ulcer polypeptides containing L-aspartic acid and intermediates thereto G. D. SEARLE & CO. (US) 1977-03-15 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250051306-A1 RAS INHIBITORS KRAS, NRAS, HRAS SLC15A1 4488/4885ALDH1A1 4437/4885MAPK1 352/4885
US-20250195521-A1 USE OF SOS1 INHIBITORS TO TREAT MALIGNANCIES WITH SHP2 MUTATIONS SOS1, PPM1D, PTPN1 SLC15A1 3574/4885ALDH1A1 4135/4885MAPK1 202/4885
US-20240262847-A1 COVALENT RAS INHIBITORS AND USES THEREOF KRAS, NRAS, HRAS SLC15A1 4018/4885ALDH1A1 3445/4885MAPK1 284/4885
US-12252497-B2 Ras inhibitors KRAS, NRAS, HRAS SLC15A1 4309/4885ALDH1A1 4520/4885MAPK1 315/4885
US-20240277796-A1 METHODS FOR INHIBITING RAS KRAS, HRAS, NRAS SLC15A1 4463/4885ALDH1A1 4355/4885MAPK1 1648/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.