Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC15A1 | P46059 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | IDO1 | P14902 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | CDC25B | P30305 | 1/20 | 0.48 |
| ▸ | LTA4H | P09960 | 1/20 | 0.47 |
| ▸ | LAP3 | P28838 | 1/20 | 0.47 |
| ▸ | SLC1A1 | P43005 | 3/20 | 0.46 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.46 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL589203 | 1.00 | SLC15A1 (0.61) | SLC15A1ALDH1A1MAPK1L3MBTL1IDO1 | |
| SCHEMBL1264374 | 1.00 | SLC15A1 (0.61) | SLC15A1ALDH1A1MAPK1L3MBTL1IDO1 | |
| SCHEMBL32681189 | 1.00 | SLC15A1 (0.61) | SLC15A1ALDH1A1MAPK1L3MBTL1IDO1 | |
| Hydrochloric Acid SCHEMBL29401429 | 0.98 | SLC15A1 (0.59) | SLC15A1ALDH1A1MAPK1L3MBTL1IDO1 | |
| Hydrochloric Acid SCHEMBL16987449 | 0.98 | SLC15A1 (0.59) | SLC15A1ALDH1A1MAPK1L3MBTL1IDO1 | |
| Hydrochloric Acid SCHEMBL14762001 | 0.98 | SLC15A1 (0.59) | SLC15A1ALDH1A1MAPK1L3MBTL1IDO1 | |
| SCHEMBL28820464 | 0.92 | SLC15A1 (0.52) | SLC15A1ALDH1A1MAPK1L3MBTL1IDO1 | |
| Aspartic Acid SCHEMBL28852564 | 0.91 | SLC15A1 (0.56) | SLC15A1ALDH1A1MAPK1L3MBTL1IDO1 | |
| SCHEMBL28154515 | 0.91 | SLC15A1 (0.52) | SLC15A1ALDH1A1MAPK1L3MBTL1IDO1 | |
| SCHEMBL8413846 | 0.91 | SLC15A1 (0.56) | SLC15A1ALDH1A1MAPK1L3MBTL1IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260125379-A1 | PRODRUG OF JAK KINASE INHIBITOR | E NITIATE BIOPHARMACEUTICALS HANGZHOU CO LTD (CN) | 2026-05-07 | — | — | US | disclosed |
| US-20260091082-A1 | CYCLIC PEPTIDE DERIVATIVE COMPOSITION FOR TREATING OR PREVENTING EYE DISEASE | DKS CO. LTD. (JP) | 2026-04-02 | — | — | US | disclosed |
| US-20260035407-A1 | CYCLIC PEPTIDE DERIVATIVE, METHOD FOR PRODUCING SAME, AND COMPOSITION | DKS CO. LTD. (JP) | 2026-02-05 | — | — | US | disclosed |
| EP-3700578-B1 | SYSTEMS FOR RENAL FUNCTION DETERMINATION | MEDIBEACON INC (US) | 2025-12-03 | — | — | EP | disclosed |
| EP-4582425-A1 | PRODRUG OF JAK KINASE INHIBITOR | E-nitiate Biopharmaceuticals (Hangzhou) Co., Ltd (CN) | 2025-07-09 | — | — | EP | disclosed |
| US-12303570-B2 | Compositions and methods for assessing eye vasculature | MEDIBEACON INC. (US) | 2025-05-20 | — | — | US | disclosed |
| EP-4425181-A1 | COMPOSITION FOR DETECTING OR MEASURING ANALYTE | Bertis Inc (KR) | 2024-09-04 | — | — | EP | disclosed |
| WO-2024041586-A1 | PRODRUG OF JAK KINASE INHIBITOR | 启元生物(杭州)有限公司 | 2024-02-29 | — | — | WO | disclosed |
| US-20240011979-A1 | COMPOSITION FOR DETECTING OR MEASURING ANALYTES | BERTIS INC. (KR) | 2024-01-11 | — | — | US | disclosed |
| US-20230173111-A1 | COMPOSITIONS AND SYSTEMS FOR RENAL FUNCTION DETERMINATION | MEDIBEACON INC. | 2023-06-08 | — | — | US | disclosed |
| US-9114160-B2 | Pyrazine derivatives and uses thereof in renal monitoring | Medibeacon, LLC (US) | 2015-08-25 | — | — | US | disclosed |
| US-20140286874-A1 | Pyrazine Derivatives and Uses Thereof in Renal Monitoring | MEDIBEACON, INC. | 2014-09-25 | — | — | US | disclosed |
| US-8722685-B2 | Pyrazine derivatives and uses thereof in renal monitoring | Medibeacon, LLC (US) | 2014-05-13 | — | — | US | disclosed |
| EP-2029554-B1 | PYRAZINE DERIVATIVES AND USES THEREOF IN RENAL MONITORING | MEDIBEACON LLC (US) | 2014-03-19 | — | — | EP | disclosed |
| US-20120100078-A1 | Pyrazine Derivatives and Uses Thereof in Renal Monitoring | MALLINCKRODT LLC (US) | 2012-04-26 | — | — | US | disclosed |
| US-8115000-B2 | Pyrazine derivatives and uses thereof in renal monitoring | MALLINCKRODT LLC (US) | 2012-02-14 | — | — | US | disclosed |
| US-20090198053-A1 | Pyrazine Derivatives and Uses Thereof in Renal Monitoring | MEDIBEACON INC. | 2009-08-06 | — | — | US | disclosed |
| EP-2029554-A1 | PYRAZINE DERIVATIVES AND USES THEREOF IN RENAL MONITORING | Mallinckrodt, Inc. (US) | 2009-03-04 | — | — | EP | disclosed |
| CN-101351454-A | Pyrazine derivatives and their use in renal monitoring | MALLINCKRODT INC (US) | 2009-01-21 | — | — | CN | disclosed |
| WO-2007149479-A1 | PYRAZINE DERIVATIVES AND USES THEREOF IN RENAL MONITORING | MALLINCKRODT INC. (US) | 2007-12-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260091082-A1 | CYCLIC PEPTIDE DERIVATIVE COMPOSITION FOR TREATING OR PREVENTING EYE DISEASE | ADCY3, GLP1R, PDE6C | SLC15A1 1755/4885ALDH1A1 2607/4885MAPK1 509/4885 |
| US-20260035407-A1 | CYCLIC PEPTIDE DERIVATIVE, METHOD FOR PRODUCING SAME, AND COMPOSITION | BDNF, VIP, CA3 | SLC15A1 1688/4885ALDH1A1 2934/4885MAPK1 443/4885 |
| US-20140286874-A1 | Pyrazine Derivatives and Uses Thereof in Renal Monitoring | CYP3A5, GLS, XDH | SLC15A1 622/4885ALDH1A1 265/4885MAPK1 1394/4885 |
| US-20230173111-A1 | COMPOSITIONS AND SYSTEMS FOR RENAL FUNCTION DETERMINATION | GLS, ATP6V1B1, REN | SLC15A1 218/4885ALDH1A1 3528/4885MAPK1 3824/4885 |
| US-20260125379-A1 | PRODRUG OF JAK KINASE INHIBITOR | JAK1, JAK2, JAK3 | SLC15A1 1555/4885ALDH1A1 1710/4885MAPK1 116/4885 |
| US-20120100078-A1 | Pyrazine Derivatives and Uses Thereof in Renal Monitoring | CYP3A5, GLS, XDH | SLC15A1 622/4885ALDH1A1 265/4885MAPK1 1394/4885 |
| US-20090198053-A1 | Pyrazine Derivatives and Uses Thereof in Renal Monitoring | GLS, CYP3A5, PYCR1 | SLC15A1 596/4885ALDH1A1 268/4885MAPK1 1318/4885 |
| US-12303570-B2 | Compositions and methods for assessing eye vasculature | LIPG, FLT4, FABP3 | SLC15A1 2301/4885ALDH1A1 1933/4885MAPK1 4862/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.