SCHEMBL4523936

SCHEMBL4523936

NC(CC(=O)OCc1ccccc1)C(=O)O

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC15A1 P46059 2/20 0.65
ALDH1A1 P00352 3/20 0.58
MAPK1 P28482 1/20 0.58
L3MBTL1 Q9Y468 1/20 0.58
SLC1A1 P43005 6/20 0.56
SLC1A3 P43003 5/20 0.55
ALPI P09923 1/20 0.55
PKM P14618 1/20 0.55
PTGS1 P23219 1/20 0.55
XIAP P98170 1/20 0.55
SLC7A5 Q01650 1/20 0.55
LTA4H P09960 1/20 0.52
SLC1A2 P43004 4/20 0.51
KMT2A Q03164 2/20 0.50
MEN1 O00255 1/20 0.50
CYP1A2 P05177 1/20 0.50
CYP2D6 P10635 1/20 0.50
CYP2C9 P11712 1/20 0.50
CYP2C19 P33261 1/20 0.50
GRIK1 P39086 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5898461 1.00 SLC15A1 (0.65) SLC15A1ALDH1A1MAPK1L3MBTL1SLC1A1
SCHEMBL730848 1.00 SLC15A1 (0.65) SLC15A1ALDH1A1MAPK1L3MBTL1SLC1A1
Hydrochloric Acid SCHEMBL14482670 0.98 SLC15A1 (0.63) SLC15A1ALDH1A1MAPK1L3MBTL1SLC1A1
Hydrochloric Acid SCHEMBL14482674 0.98 SLC15A1 (0.63) SLC15A1ALDH1A1MAPK1L3MBTL1SLC1A1
Phenylalanine SCHEMBL744817 0.94 SLC15A1 (0.71) SLC15A1ALDH1A1MAPK1L3MBTL1SLC1A1
Aspartic Acid SCHEMBL28852564 0.91 SLC15A1 (0.56) SLC15A1ALDH1A1MAPK1L3MBTL1SLC1A1
SCHEMBL589203 0.90 SLC15A1 (0.61) SLC15A1ALDH1A1MAPK1L3MBTL1SLC1A1
SCHEMBL1264374 0.90 SLC15A1 (0.61) SLC15A1ALDH1A1MAPK1L3MBTL1SLC1A1
SCHEMBL589202 0.90 SLC15A1 (0.61) SLC15A1ALDH1A1MAPK1L3MBTL1SLC1A1
SCHEMBL32681189 0.90 SLC15A1 (0.61) SLC15A1ALDH1A1MAPK1L3MBTL1SLC1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 112 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115960154-A 20-hydroxyprogesterone precursor compound and preparation method and application thereof 新疆医科大学 2023-04-14 CN claimed
CN-112010935-B Acetyl RGD modified hexacyclic piperazinedione, preparation, anti-tumor activity and application thereof 首都医科大学 2022-08-05 CN claimed
CN-112010934-B Acetyl RGD modified hexacyclic piperazinedione, preparation, transfer-resistant activity and application thereof 首都医科大学 2022-08-02 CN claimed
CN-112010938-B Acetyl RGD modified hexacyclic piperazinedione, preparation, anti-inflammatory activity and application thereof 首都医科大学 2022-08-02 CN claimed
CN-112029091-B PH/reduction dual-responsiveness block copolymer PEG-b-PASp-g-CPA 中国药科大学 2022-06-10 CN claimed
CN-112472672-B Polypeptide-polysaccharide graft copolymer based platinum nano prodrug and preparation method and application thereof 西安交通大学 2022-01-25 CN claimed
CN-109535225-A A kind of compound and its synthetic method and application 暨南大学 2019-03-29 CN claimed
EP-1976873-A2 HUMAN GLUCAGON-LIKE-PEPTIDE-1 MODULATORS AND THEIR USE IN THE TREATMENT OF DIABETES AND RELATED CONDITIONS Brystol-Myers Squibb Company (US) 2008-10-08 EP claimed
US-20070238669-A1 HUMAN GLUCAGON-LIKE-PEPTIDE-1 MODULATORS AND THEIR USE IN THE TREATMENT OF DIABETES RELATED CONDITIONS BRISTOL-MYERS SQUIBB COMPANY 2007-10-11 US claimed
WO-2007082264-A2 HUMAN GLUCAGON-LIKE-PEPTIDE-1 MODULATORS AND THEIR USE IN THE TREATMENT OF DIABETES AND RELATED CONDITIONS BRISTOL-MYERS SQUIBB COMPANY (US) 2007-07-19 WO claimed
JP-3118354-A None JP disclosed
CN-120965997-A Preparation method of amphiphilic polyamino acid drug carrier 宁德师范学院 2025-11-18 CN disclosed
WO-2025064683-A1 SMALL MOLECULE PROTEIN SYNTHESIS MODULATORS Interdict Bio, Inc. (US) 2025-03-27 WO disclosed
US-20250091989-A1 SMALL MOLECULE PROTEIN SYNTHESIS MODULATORS Interdict Bio, Inc. (US) 2025-03-20 US disclosed
US-20250025438-A1 Derivative of aspartic acid and use thereof in treatment of metabolic diseases such as hepatic fibrosis and non-alcoholic hepatitis SHENZHEN JINGTAI TECHNOLOGY CO., LTD. (CN) 2025-01-23 US disclosed
EP-0205031-A1 Process for the preparation of aspartic acid 4-benzyl ester HOECHST AKTIENGESELLSCHAFT (DE) 1986-12-17 EP disclosed
CN-86103943-A The preparation method of aspartic acid 4-benzyl ester 1986-12-10 CN disclosed
CN-86103943-A The preparation method of aspartic acid 4-benzyl ester 1986-12-10 CN disclosed
CN-86103943-A The preparation method of aspartic acid 4-benzyl ester 1986-12-10 CN disclosed
US-3934027-A 18β-Glycyrrhetinic acid amides useful as antiulcer agents PFIZER INC. (US) 1976-01-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070238669-A1 HUMAN GLUCAGON-LIKE-PEPTIDE-1 MODULATORS AND THEIR USE IN THE TREATMENT OF DIABETES RELATED CONDITIONS GLP1R, GIPR, IAPP SLC15A1 1493/4885ALDH1A1 4570/4885MAPK1 2059/4885
US-20250091989-A1 SMALL MOLECULE PROTEIN SYNTHESIS MODULATORS MYC, KRAS, NRAS SLC15A1 3793/4885ALDH1A1 2774/4885MAPK1 269/4885
US-20250025438-A1 Derivative of aspartic acid and use thereof in treatment of metabolic diseases such as hepatic fibrosis and non-alcoholic hepatitis GOT1, GOT2, GLS2 SLC15A1 207/4885ALDH1A1 38/4885MAPK1 1578/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.