Phenylalanine

Phenylalanine

SCHEMBL744817

N[C@@H](CC(=O)OCc1ccccc1)C(=O)O.N[C@@H](Cc1ccccc1)C(=O)O

nearest known ligand 0.71

Full drug profile on Sugi Atlas →

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
SLC15A1 P46059 3/20 0.71
SLC7A5 Q01650 4/20 0.67
ALPI P09923 1/20 0.67
PKM P14618 1/20 0.67
PTGS1 P23219 1/20 0.67
XIAP P98170 1/20 0.67
SLC1A1 P43005 3/20 0.54
SLC1A3 P43003 2/20 0.54
SLC1A2 P43004 1/20 0.54
ALDH1A1 P00352 2/20 0.51
MAPK1 P28482 1/20 0.51
L3MBTL1 Q9Y468 1/20 0.51
LTA4H P09960 2/20 0.48
GRIA2 P42262 1/20 0.48
LAP3 P28838 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5898461 0.94 SLC15A1 (0.65) SLC15A1SLC7A5ALPIPKMPTGS1
SCHEMBL730848 0.94 SLC15A1 (0.65) SLC15A1SLC7A5ALPIPKMPTGS1
SCHEMBL4523936 0.94 SLC15A1 (0.65) SLC15A1SLC7A5ALPIPKMPTGS1
Hydrochloric Acid SCHEMBL14482674 0.92 SLC15A1 (0.63) SLC15A1SLC7A5ALPIPKMPTGS1
Hydrochloric Acid SCHEMBL14482670 0.92 SLC15A1 (0.63) SLC15A1SLC7A5ALPIPKMPTGS1
Aspartic Acid SCHEMBL28852564 0.85 SLC15A1 (0.56) SLC15A1SLC7A5ALPIPKMPTGS1
SCHEMBL14768478 0.84 SLC15A1 (0.62) SLC15A1SLC7A5ALPIPKMPTGS1
SCHEMBL10140601 0.84 SLC15A1 (0.62) SLC15A1SLC7A5ALPIPKMPTGS1
SCHEMBL589202 0.84 SLC15A1 (0.61) SLC15A1SLC7A5ALPIPKMPTGS1
SCHEMBL32681189 0.84 SLC15A1 (0.61) SLC15A1SLC7A5ALPIPKMPTGS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2431403-B1 POLYMER CONJUGATE OF BIOACTIVE SUBSTANCE HAVING HYDROXY GROUP NIPPON KAYAKU KK (JP) 2016-09-28 EP disclosed
EP-2431403-A1 POLYMER CONJUGATE OF BIOACTIVE SUBSTANCE HAVING HYDROXY GROUP Nippon Kayaku Kabushiki Kaisha (JP) 2012-03-21 EP disclosed