Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 8/20 | 0.54 |
| ▸ | MMP13 | P45452 | 8/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | ACLY | P53396 | 1/20 | 0.48 |
| ▸ | USP5 | P45974 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | FPR2 | P25090 | 1/20 | 0.43 |
| ▸ | PROKR1 | Q8TCW9 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6572436 | 0.94 | MMP2 (0.53) | MMP2MMP13KMT2AACLYUSP5 | |
| SCHEMBL8363785 | 0.92 | MMP2 (0.51) | MMP2MMP13KMT2ASMN1; SMN2MAPT | |
| SCHEMBL5898959 | 0.91 | MMP2 (0.48) | MMP2MMP13KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL8361646 | 0.91 | MMP2 (0.51) | MMP2MMP13KMT2AACLYSMN1; SMN2 | |
| SCHEMBL8361708 | 0.90 | MMP2 (0.52) | MMP2MMP13KMT2ASMN1; SMN2MAPT | |
| SCHEMBL5898961 | 0.90 | MMP2 (0.52) | MMP2MMP13KMT2AACLYSMN1; SMN2 | |
| SCHEMBL7431658 | 0.88 | ACLY (0.49) | MMP2MMP13KMT2AACLYUSP5 | |
| SCHEMBL5898986 | 0.88 | MMP13 (0.69) | MMP2MMP13KMT2ASMN1; SMN2MAPT | |
| SCHEMBL8361679 | 0.88 | MMP13 (0.64) | MMP2MMP13KMT2ASMN1; SMN2MAPT | |
| SCHEMBL5898980 | 0.87 | MMP13 (0.49) | MMP2MMP13KMT2ASMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7115632-B1 | Sulfonyl aryl or heteroaryl hydroxamic acid compounds | G. D. SEARLE & CO. (US) | 2006-10-03 | — | — | US | disclosed |
| WO-2003007954-A2 | SULFONYL ARYL HYDROXAMATES AND THEIR USE AS MATRIX METALLOPROTEASE INHIBITORS | PHARMACIA CORPORATION (US) | 2003-01-30 | — | — | WO | disclosed |