Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | FOLH1 | Q04609 | 7/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.35 |
| ▸ | PLA2G5 | P39877 | 2/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | MME | P08473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5899071 | 0.83 | TSHR (0.51) | TSHRTDP1ALDH1A1GAAEPHX2 | |
| SCHEMBL10501285 | 0.77 | TSHR (0.51) | TSHRTDP1ALDH1A1GAAEPHX2 | |
| SCHEMBL8100012 | 0.77 | TSHR (0.51) | TSHRTDP1ALDH1A1GAAEPHX2 | |
| SCHEMBL10606206 | 0.77 | TSHR (0.51) | TSHRTDP1ALDH1A1GAAEPHX2 | |
| SCHEMBL6432779 | 0.74 | ALDH1A1 (0.41) | ALDH1A1FOLH1MEN1LMNAKMT2A | |
| SCHEMBL2511764 | 0.74 | ALDH1A1 (0.53) | ALDH1A1FOLH1MEN1LMNAKMT2A | |
| SCHEMBL2402155 | 0.74 | ALDH1A1 (0.51) | ALDH1A1FOLH1MEN1LMNAKMT2A | |
| SCHEMBL8951293 | 0.74 | ALDH1A1 (0.51) | ALDH1A1FOLH1MEN1LMNAKMT2A | |
| SCHEMBL12629241 | 0.73 | TSHR (0.61) | TSHRTDP1ALDH1A1GAAEPHX2 | |
| SCHEMBL28931215 | 0.73 | TSHR (0.61) | TSHRTDP1ALDH1A1GAAEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7045592-B2 | Processes for coupling amino acids using bis-(trichloromethyl) carbonate | DEVELOGEN ISRAEL LTD. (IL) | 2006-05-16 | — | — | US | disclosed |
| US-20030195331-A1 | Processes for coupling amino acids using bis-(trichloromethyl) carbonate | PEPTOR LTD. (IL) | 2003-10-16 | — | — | US | disclosed |
| US-6512092-B2 | Solid phase peptide synthesis; in situ generation of amino acid chloride by deblocking; coupling sterically hindered amino acid residues | PEPTOR LTD. (IL) | 2003-01-28 | — | — | US | disclosed |
| US-20010007037-A1 | Processes for coupling amino acids using bis-(trichloromethyl) carbonate | FALB ELIEZER (IL) | 2001-07-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010007037-A1 | Processes for coupling amino acids using bis-(trichloromethyl) carbonate | PTMS, BCAT1, DAO | TSHR 453/4885TDP1 2191/4885ALDH1A1 4814/4885 |
| US-20030195331-A1 | Processes for coupling amino acids using bis-(trichloromethyl) carbonate | PTMS, BCAT1, DAO | TSHR 453/4885TDP1 2191/4885ALDH1A1 4814/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.