Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 5/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | HTT | P42858 | 3/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.48 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.48 |
| ▸ | MITF | O75030 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1937924 | 0.81 | CYP19A1 (0.58) | ALDH1A1MAPTGAAMEN1KMT2A | |
| SCHEMBL23014272 | 0.81 | KMT2A (0.64) | ALDH1A1MAPTGAAMEN1KMT2A | |
| SCHEMBL5320468 | 0.81 | MMP1 (0.56) | ALDH1A1RAB9AMAPTSMN1; SMN2GAA | |
| SCHEMBL1938386 | 0.79 | HPGD (0.55) | ALDH1A1RAB9AMAPTSMN1; SMN2HPGD | |
| SCHEMBL5899423 | 0.79 | AKR1C3 (0.49) | ALDH1A1SMN1; SMN2HPGDMEN1KMT2A | |
| SCHEMBL11698130 | 0.78 | TP53 (0.58) | ALDH1A1RAB9AMAPTSMN1; SMN2HPGD | |
| SCHEMBL4426596 | 0.78 | KMT2A (0.51) | ALDH1A1MAPTSMN1; SMN2GAAHPGD | |
| SCHEMBL4432418 | 0.77 | CYP1A2 (0.56) | ALDH1A1MAPTGAAMEN1KMT2A | |
| SCHEMBL5489641 | 0.77 | TSHR (0.56) | ALDH1A1MAPTGAAMEN1KMT2A | |
| SCHEMBL14861394 | 0.76 | CYP1A2 (0.49) | ALDH1A1MAPTSMN1; SMN2GAAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060025445-A1 | 11-Beta HSD1 inhibitors | WYETH | 2006-02-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060025445-A1 | 11-Beta HSD1 inhibitors | HSD11B1, HSD11B2, HSD3B1 | ALDH1A1 139/4885RAB9A 3734/4885MAPT 3655/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.