Known targets — ChEMBL curated mechanism
ADRA1AADRA1BADRA1DADRB1ADRB2ADRB3CYP11B1DPP4FGFR1FGFR2FGFR3FGFR4HRH1JAK1JAK2JAK3KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITNAOPRD1OPRK1OPRM1PPDGFRBPIK3CDSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASMOTYK2polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Glycerin. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.60 |
| ▸ | THRB | P10828 | 2/20 | 0.40 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.35 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.35 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.35 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.32 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MMP2 | P08253 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Glycerin SCHEMBL468814 | 1.00 | LMNA (0.60) | LMNAALDH1A1THRBGABRR1GABBR2 | |
| Glycerin SCHEMBL27232528 | 1.00 | LMNA (0.60) | LMNAALDH1A1THRBGABRR1GABBR2 | |
| Glycerin SCHEMBL30710214 | 0.97 | LMNA (0.64) | LMNAALDH1A1THRBGABRR1GABBR2 | |
| Glycerin SCHEMBL188342 | 0.97 | LMNA (0.64) | LMNAALDH1A1THRBGABRR1GABBR2 | |
| Glycerin SCHEMBL21101 | 0.97 | LMNA (0.64) | LMNAALDH1A1THRBGABRR1GABBR2 | |
| Glycerin SCHEMBL579432 | 0.97 | LMNA (0.64) | LMNAALDH1A1THRBGABRR1GABBR2 | |
| Glycerin SCHEMBL888512 | 0.97 | LMNA (0.64) | LMNAALDH1A1THRBGABRR1GABBR2 | |
| Glycerin SCHEMBL31106042 | 0.97 | LMNA (0.64) | LMNAALDH1A1THRBGABRR1GABBR2 | |
| Glycerin SCHEMBL14482185 | 0.93 | LMNA (0.60) | LMNAALDH1A1THRBGABRR1GABBR2 | |
| Glycerin SCHEMBL1792712 | 0.93 | LMNA (0.60) | LMNAALDH1A1THRBGABRR1GABBR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004098294-A1 | DOUGH ADDITIVE | BRECHET & RICHTER COMPANY (US) | 2004-11-18 | — | — | WO | claimed |
| US-20040028782-A1 | Microwave baking additive | BRECHET & RICHTER COMPANY (US) | 2004-02-12 | — | — | US | claimed |
| US-6579546-B1 | Controlling moisture migration or starch crystallization in baked goods by adding gels, gums and enzymes, then baking in microwaves | BRECHET & RICHTER COMPANY | 2003-06-17 | — | — | US | claimed |
| US-20060275223-A1 | Erythritol compositions for teeth and gums | XLEAR, INC. | 2006-12-07 | — | — | US | disclosed |
| WO-2004112486-A2 | MICROWAVE BAKING ADDITIVE | BRECHET & RICHTER COMPANY (US) | 2004-12-29 | — | — | WO | disclosed |
| WO-2004098294-A1 | DOUGH ADDITIVE | BRECHET & RICHTER COMPANY (US) | 2004-11-18 | — | — | WO | disclosed |
| US-20040028782-A1 | Microwave baking additive | BRECHET & RICHTER COMPANY (US) | 2004-02-12 | — | — | US | disclosed |
| US-20030206994-A1 | Microwave baking additive | BRECHET & RICHTER COMPANY | 2003-11-06 | — | — | US | disclosed |
| US-6579546-B1 | Controlling moisture migration or starch crystallization in baked goods by adding gels, gums and enzymes, then baking in microwaves | BRECHET & RICHTER COMPANY | 2003-06-17 | — | — | US | disclosed |