Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 4/20 | 0.45 |
| ▸ | ADRA1D | P25100 | 6/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 6/20 | 0.44 |
| ▸ | ADRA1B | P35368 | 6/20 | 0.44 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.44 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.44 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | HTR7 | P34969 | 1/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.44 |
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
| ▸ | HTR2B | P41595 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | LDHA | P00338 | 1/20 | 0.40 |
| ▸ | FPR2 | P25090 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5807725 | 1.00 | ACACB (0.45) | ACACBADRA1DADRA1AADRA1BADRB2 | |
| SCHEMBL5059309 | 0.89 | ADRA1D (0.56) | ACACBADRA1DADRA1AADRA1BADRB2 | |
| SCHEMBL5059304 | 0.89 | ADRA1D (0.56) | ACACBADRA1DADRA1AADRA1BADRB2 | |
| SCHEMBL24503566 | 0.79 | TRPV4 (0.45) | ADRA1DADRA1AADRA1BADRB2ADRB1 | |
| SCHEMBL14300657 | 0.78 | ADRA1D (0.53) | ACACBADRA1DADRA1AADRA1BADRB2 | |
| SCHEMBL5052802 | 0.78 | ADRA1D (0.53) | ACACBADRA1DADRA1AADRA1BADRB2 | |
| SCHEMBL5052805 | 0.78 | ADRA1D (0.53) | ACACBADRA1DADRA1AADRA1BADRB2 | |
| SCHEMBL14370514 | 0.76 | ACACB (0.58) | ACACBADRA1DADRA1AADRA1BADRB2 | |
| SCHEMBL12323563 | 0.76 | ACACB (0.58) | ACACBADRA1DADRA1AADRA1BADRB2 | |
| SCHEMBL5806232 | 0.75 | ACACB (0.60) | ACACBLDHAFPR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060148046-A1 | Enzymatic process for the preparation of an intermediate compound and use thereof for the synthesis of tamsulosin hydrochloride | QUIMICA SINTETICA, S.A. | 2006-07-06 | — | — | US | disclosed |